Methyl 2-[(4-chlorophenyl)acetyl]benzoate

Base Information

• Chemical Name: Methyl 2-[(4-chlorophenyl)acetyl]benzoate
• CAS No.: 61653-04-1
• Molecular Formula: C16H13ClO3
• Molecular Weight: 288.73
• DSSTox Substance ID: DTXSID40521224
• Nikkaji Number: J511.863H
• Wikidata: Q82385580

Synonyms:61653-04-1;Methyl 2-[(4-chlorophenyl)acetyl]benzoate;DTXSID40521224

Chemical Property of Methyl 2-[(4-chlorophenyl)acetyl]benzoate

Chemical Property:

• Boiling Point: 430.0±30.0 °C(Predicted)
• PSA: 43.37000
• Density: 1.247±0.06 g/cm3(Predicted)
• LogP: 3.55200
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 288.0553220
• Heavy Atom Count: 20
• Complexity: 348

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(=O)C1=CC=CC=C1C(=O)CC2=CC=C(C=C2)Cl

Technology Process of Methyl 2-[(4-chlorophenyl)acetyl]benzoate

There total 3 articles about Methyl 2-[(4-chlorophenyl)acetyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.0%

1-Chloro-4-(chloromethyl)benzene (104-83-6) → benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + 1,2-bis(4-chlorophenyl)ethane (5216-35-3) + diphenic acid dimethyl ester (5807-64-7) + methyl 2-(4-chlorophenylacetyl)benzoate (61653-04-1)

Guidance literature:

With carbon monoxide; o-iodo-methyl-benzoic acid; copper; zinc; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; under 760 Torr; Further byproducts given; -78 deg C, 2h; room temp., 1 h; 60 deg C, 6 h;

DOI:10.1016/S0040-4039(00)94298-9

Reference yield: 28.0%

carbon monoxide (201230-82-2) + o-iodo-methyl-benzoic acid (610-97-9) + 1-Chloro-4-(chloromethyl)benzene (104-83-6) → benzoic acid methyl ester (93-58-3,5705-52-2,80226-58-0) + 1,2-bis(4-chlorophenyl)ethane (5216-35-3) + diphenic acid dimethyl ester (5807-64-7) + methyl 2-(4-chlorophenylacetyl)benzoate (61653-04-1)

Guidance literature:

With copper; zinc; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; under 760 Torr; Further byproducts given; -78 deg C, 2h; room temp., 1 h; 60 deg C, 6 h;

DOI:10.1016/S0040-4039(00)94298-9

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 2‐(4-chlorophenylacetyl)benzoic acid (53242-76-5) → methyl 2-(4-chlorophenylacetyl)benzoate (61653-04-1)

Guidance literature:

In diethyl ether;

DOI:10.1039/P29860002031

upstream raw materials:

diazomethane

2‐(4-chlorophenylacetyl)benzoic acid

carbon monoxide

o-iodo-methyl-benzoic acid

Downstream raw materials:

methanol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 61653-04-1 Benzoic acid, 2-[(4-chlorophenyl)acetyl]-, methyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send