2-(Trifluoromethyl)pyrazine

Base Information

Chemical Name:2-(Trifluoromethyl)pyrazine
CAS No.:61655-67-2
Molecular Formula:C5H3F3N2
Molecular Weight:148.08600
Hs Code.:2933990090
European Community (EC) Number:662-953-4
DSSTox Substance ID:DTXSID60591489
Nikkaji Number:J3.279.852G
Wikidata:Q82485266
Mol file:61655-67-2.mol

Synonyms:2-(trifluoromethyl)pyrazine;61655-67-2;2-trifluoromethylpyrazine;2-(trifluoromethyl)-pyrazine;MFCD06797734;Pyrazine, (trifluoromethyl)-;starbld0016883;2-Trifluoromethyl-pyrazine;SCHEMBL631338;Pyrazine, 2-(trifluoromethyl)-;DTXSID60591489;CEAMSISEJZMQEP-UHFFFAOYSA-N;HBNXASFAWUTHHD-UHFFFAOYSA-N;UUOBJRAZARPAQM-UHFFFAOYSA-N;2-(Trifluoromethyl)pyrazine, 97%;BBL103662;STL557472;AKOS005259003;CS-W018192;FS-5375;DA-27565;AM20070373;EN300-102249;F11354;A849544

Suppliers and Price of 2-(Trifluoromethyl)pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Trifluoromethyl)pyrazine
1g
$ 200.00

SynQuest Laboratories
2-(Trifluoromethyl)pyrazine
10 g
$ 820.00

SynQuest Laboratories
2-(Trifluoromethyl)pyrazine
5 g
$ 436.00

Sigma-Aldrich
2-(Trifluoromethyl)pyrazine 97%
1g
$ 130.00

Oakwood
2-(Trifluoromethyl)-pyrazine 98%
25g
$ 1290.00

Matrix Scientific
2-(Trifluoromethyl)pyrazine 97%
1g
$ 119.00

Matrix Scientific
2-(Trifluoromethyl)pyrazine 97%
500mg
$ 77.00

Matrix Scientific
2-(Trifluoromethyl)pyrazine 97%
5g
$ 417.00

Chemenu
2-(Trifluoromethyl)pyrazine 95%+
10g
$ 921.00

Chemenu
2-(Trifluoromethyl)pyrazine 95%+
5g
$ 551.00

Total 24 raw suppliers

Chemical Property of 2-(Trifluoromethyl)pyrazine

Chemical Property:

Refractive Index:n20/D1.417
Boiling Point:116-118℃
PKA:-1.11±0.10(Predicted)
Flash Point:33℃
PSA：25.78000
Density:1.344 g/mL at 25 °C
LogP:1.49540
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:148.02483259
Heavy Atom Count:10
Complexity:112

Purity/Quality:

97% ^*data from raw suppliers

2-(Trifluoromethyl)pyrazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:T
Statements: 10-25-36/37/38
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=C(C=N1)C(F)(F)F

Technology Process of 2-(Trifluoromethyl)pyrazine

There total 10 articles about 2-(Trifluoromethyl)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 61655-67-2
2-(trifluoromethyl)pyrazine

Guidance literature:: With 1,3-dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone; copper(l) chloride; at 50 ℃; for 24h; Inert atmosphere;

Reference yield:

: 109-08-0
2-Methylpyrazine

: N-methyl-2-phenyl-2-trifluoromethylbenzimidazoline

: 61655-67-2
2-(trifluoromethyl)pyrazine

Guidance literature:: With [2,2]bipyridinyl; copper(l) iodide; potassium carbonate; In benzonitrile; at 90 ℃; for 48h;
DOI:10.3762/BJOC.16.198

Reference yield:

: 56423-63-3
2-bromopyrazine

: 1895006-01-5
dimesityl(trifluoromethyl)sulfonium trifluoromethanesulfonate

: 61655-67-2
2-(trifluoromethyl)pyrazine

Guidance literature:: With dilithium tetrabromocuprate; 1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)-2-trisilanol; Ir(2-(2,4-difluorophenyl)-5-fluoropyridine)₂(4,4'-di(trifluoromethyl)-2,2'-bipyridyl)PF₆; sodium carbonate; In acetone; at 35 ℃; Irradiation;
DOI:10.1126/science.aat4133