2,6-Dichloromethyl pyridine hydrochloride

Base Information

• Chemical Name: 2,6-Dichloromethyl pyridine hydrochloride
• CAS No.: 3099-50-1
• Molecular Formula: C6H4 Cl3 N
• Molecular Weight: 196.463
• Hs Code.: 2933399090
• Mol file: 3099-50-1.mol

Synonyms:3-(Trichloromethyl)pyridine

Chemical Property of 2,6-Dichloromethyl pyridine hydrochloride

Chemical Property:

• Boiling Point: 245℃
• PKA: 2.84±0.11(Predicted)
• Flash Point: 126℃
• PSA: 12.89000
• Density: 1.466
• LogP: 3.36120
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-(Trichloromethyl)pyridine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Dichloromethyl pyridine hydrochloride

There total 6 articles about 2,6-Dichloromethyl pyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nicotinic acid (59-67-6) → 3-trichloromethyl-pyridine (3099-50-1) + 2-chloro-5-(Trichloromethyl)-pyridine (69045-78-9) + 2,3-dichloro-5-(trichloromethyl)pyridine (69045-83-6)

Guidance literature:

With phosphorus pentachloride; at 185 ℃; for 72h; under 18751.9 - 30003 Torr; Temperature; Autoclave;

Reference yield:

nicotinic acid (59-67-6) → 5-chloro-3-trichloromethyl pyridine + 3-trichloromethyl-pyridine (3099-50-1) + 2-chloro-5-(Trichloromethyl)-pyridine (69045-78-9) + 2,3-dichloro-5-(trichloromethyl)pyridine (69045-83-6)

Guidance literature:

With phosphorus pentachloride; at 175 ℃; for 96h; under 18751.9 - 30003 Torr; Autoclave;

Reference yield:

3-Methylpyridine (108-99-6) → 3-(dichloromethyl)pyridine (3099-51-2) + 3-trichloromethyl-pyridine (3099-50-1) + 2-chloro-5-(Trichloromethyl)-pyridine (69045-78-9)

Guidance literature:

With tetrachloromethane; at 200 - 250 ℃; for 0.00388889h; Molecular sieve; Inert atmosphere;

upstream raw materials:

3-Methylpyridine

nicotinic acid

Downstream raw materials:

diphenyldisulfane

2-chloro-5-(Trichloromethyl)-pyridine

2,3-dichloro-5-(trichloromethyl)pyridine

2-amino-3-chloro-5-(trifluoromethyl)pyridine

Refernces

• 1、 -. "A METHOD FOR PRODUCING 2,3-DICHLORO-5-(TRICHLOROMETHYL)PYRIDINE". Page/Page column 13. . Retrieved 2015/01/09.