1-(4-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid

Base Information

Chemical Name:1-(4-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid
CAS No.:62160-78-5
Molecular Formula:C17H14N2O2
Molecular Weight:278.31
Hs Code.:
DSSTox Substance ID:DTXSID10353731
Wikidata:Q82131480
ChEMBL ID:CHEMBL1489796

Synonyms:62160-78-5;1-(4-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid;5-Phenyl-1-(p-tolyl)-1H-pyrazole-3-carboxylic acid;4N-640S;MLS000521440;1-(4-methylphenyl)-5-phenylpyrazole-3-carboxylic acid;SCHEMBL1514335;CHEMBL1489796;DTXSID10353731;HMS2453I13;STL482471;AKOS001676379;SMR000131848;EU-0079586;5-Phenyl-1-(p-tolyl)-1H-pyrazole-3-carboxylicacid

Suppliers and Price of 1-(4-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-(4-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:278.105527694
Heavy Atom Count:21
Complexity:360

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2C(=CC(=N2)C(=O)O)C3=CC=CC=C3

Technology Process of 1-(4-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid

There total 4 articles about 1-(4-methylphenyl)-5-phenyl-1H-pyrazole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 235789-25-0
5-phenyl-1-p-tolyl-1H-pyrazole-3-carboxylic acid methyl ester

: 62160-78-5
5-phenyl-1-p-tolyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: With potassium hydroxide; In methanol; water; for 2h; Reflux;

Reference yield:

: 98-86-2
acetophenone

: 62160-78-5
5-phenyl-1-p-tolyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sodium methylate / methanol / 5 h / Reflux

2: hydrogenchloride / methanol; water / 6 h / Reflux

3: potassium hydroxide / methanol; water / 2 h / Reflux

With hydrogenchloride; sodium methylate; potassium hydroxide; In methanol; water;

Reference yield:

: 41167-58-2
2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid methyl ester

: 62160-78-5
5-phenyl-1-p-tolyl-1H-pyrazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / methanol; water / 6 h / Reflux

2: potassium hydroxide / methanol; water / 2 h / Reflux

With hydrogenchloride; potassium hydroxide; In methanol; water;