10-(3-(4-Isopropyl-1-piperazinyl)propyl)phenothiazine

Base Information

• Chemical Name: 10-(3-(4-Isopropyl-1-piperazinyl)propyl)phenothiazine
• CAS No.: 97921-94-3
• Molecular Formula: C₂₂H₂₉N₃S
• Molecular Weight: 367.558
• DSSTox Substance ID: DTXSID80913543
• Wikidata: Q82884175
• Mol file: 97921-94-3.mol

Synonyms:10-(3-(4-Isopropyl-1-piperazinyl)propyl)phenothiazine;P 788;97921-94-3;BRN 0043644;Phenothiazine, 10-(3-(4-isopropyl-1-piperazinyl)propyl)-;C22H29N3S;DTXSID80913543;LS-105556;10-{3-[4-(PROPAN-2-YL)PIPERAZIN-1-YL]PROPYL}-10H-PHENOTHIAZINE

Chemical Property of 10-(3-(4-Isopropyl-1-piperazinyl)propyl)phenothiazine

Chemical Property:

• Vapor Pressure: 1.53E-10mmHg at 25°C
• Boiling Point: 510.6°Cat760mmHg
• Flash Point: 262.6°C
• PSA: 35.02000
• Density: 1.122g/cm³
• LogP: 4.64620
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 367.20821911
• Heavy Atom Count: 26
• Complexity: 413

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)N1CCN(CC1)CCCN2C3=CC=CC=C3SC4=CC=CC=C42

Technology Process of 10-(3-(4-Isopropyl-1-piperazinyl)propyl)phenothiazine

There total 4 articles about 10-(3-(4-Isopropyl-1-piperazinyl)propyl)phenothiazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10H-phenothiazine (92-84-2) → 10-[3-(4-isopropyl-piperazin-1-yl)-propyl]-10H-phenothiazine (97921-94-3)

Guidance literature:

With sodium amide; xylene;

DOI:10.1007/BF01075430

Reference yield:

1-(1-methylethyl)piperazine (4318-42-7) + 10-(3-bromopropyl)phenothiazine (92357-95-4) → 10-[3-(4-isopropyl-piperazin-1-yl)-propyl]-10H-phenothiazine (97921-94-3)

Guidance literature:

With copper; potassium carbonate; xylene;

Reference yield:

10H-phenothiazine-10-propanenitrile (1698-80-2) + isopropyl-bis(2-chloroethyl)amine hydrochloride (24426-36-6) → 10-[3-(4-isopropyl-piperazin-1-yl)-propyl]-10H-phenothiazine (97921-94-3)

Guidance literature:

With cobalt; N,N-dimethyl-formamide; silver carbonate; Hydrogenation_.Reagens 4: CuCl; Reagens 5: Kupfer-Pulver;

upstream raw materials:

1-(1-methylethyl)piperazine

10-(3-bromopropyl)phenothiazine

10H-phenothiazine-10-propanenitrile

isopropyl-bis(2-chloroethyl)amine hydrochloride