(S)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)pyrrolidine

Base Information

Chemical Name:(S)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)pyrrolidine
CAS No.:85187-28-6
Molecular Formula:C9H14 N2 O2
Molecular Weight:182.222
Hs Code.:
European Community (EC) Number:286-116-4
DSSTox Substance ID:DTXSID901005642
Nikkaji Number:J310.296C
Wikidata:Q83001102
Mol file:85187-28-6.mol

Synonyms:85187-28-6;EINECS 286-116-4;(S)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)pyrrolidine;SCHEMBL5971671;DTXSID901005642;NS00064245;(5-Hydroxy-3,4-dihydro-2H-pyrrol-2-yl)(pyrrolidin-1-yl)methanone

Suppliers and Price of (S)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of (S)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)pyrrolidine

Chemical Property:

Vapor Pressure:2.17E-08mmHg at 25°C
Boiling Point:452.9°C at 760 mmHg
Flash Point:227.7°C
PSA：52.90000
Density:1.228g/cm³
LogP:0.10120
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:182.105527694
Heavy Atom Count:13
Complexity:234

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C1)C(=O)C2CCC(=O)N2
Isomeric SMILES:C1CCN(C1)C(=O)[C@@H]2CCC(=O)N2

Technology Process of (S)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)pyrrolidine

There total 3 articles about (S)-1-((5-Oxo-2-pyrrolidinyl)carbonyl)pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 123-75-1
pyrrolidine

: 511543-55-8
(2R,5S)-2-trichloromethyl-1-aza-3-oxabicyclo[3.3.0]octane-4,8-dione

: 85187-28-6,59354-66-4
(5S)-5-[(pyrrolidin-1-yl)carbonyl]pyrrolidin-2-one

Guidance literature:: In acetonitrile; at 20 ℃; for 0.166667h;
DOI:10.1016/S0957-4166(02)00579-7

Reference yield:

: 98-79-3
L-Pyroglutamic acid

: 85187-28-6,59354-66-4
(5S)-5-[(pyrrolidin-1-yl)carbonyl]pyrrolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / PTSA / toluene / 16 h / Heating

2: 95 percent / acetonitrile / 0.17 h / 20 °C

With toluene-4-sulfonic acid; In toluene; acetonitrile;
DOI:10.1016/S0957-4166(02)00579-7