4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl-

Base Information

Chemical Name:4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl-
CAS No.:64292-65-5
Molecular Formula:C₂₀H₂₃NO
Molecular Weight:293.409
Hs Code.:
DSSTox Substance ID:DTXSID90394182

Synonyms:4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl-;64292-65-5;Oprea1_197430;DTXSID90394182;1-methyl-3-ethyl-2,6-diphenyl-4-piperidone

Suppliers and Price of 4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl-

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:293.177964357
Heavy Atom Count:22
Complexity:368

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1C(N(C(CC1=O)C2=CC=CC=C2)C)C3=CC=CC=C3

Technology Process of 4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl-

There total 15 articles about 4-Piperidinone, 3-ethyl-1-methyl-2,6-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-52-7
benzaldehyde

: 107-87-9
2-Pentanone

: 74-89-5
methylamine

: 68226-07-3,146905-13-7,64292-65-5
3-ethyl-1-methyl-2,6-diphenyl-piperidin-4-one

Guidance literature:: benzaldehyde; 2-Pentanone; methylamine; In ethanol; at 20 - 60 ℃; for 12h;

With hydrogenchloride; In diethyl ether; ethanol; water; Cooling with ice;

With ammonia; In acetone;
DOI:10.1080/10426507.2020.1757672

Reference yield:

: 68226-06-2,127895-86-7,149116-44-9
3-ethyl-2,6-diphenylpiperidin-4-one

: 74-88-4
methyl iodide

: 68226-07-3,146905-13-7,64292-65-5
3-ethyl-1-methyl-2,6-diphenyl-piperidin-4-one

Guidance literature:: With potassium carbonate; In acetone; for 3h; Reflux;
DOI:10.1007/s00706-008-0021-6

Reference yield:

: 107-87-9
2-Pentanone

: 68226-07-3,146905-13-7,64292-65-5
3-ethyl-1-methyl-2,6-diphenyl-piperidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium acetate / ethanol / Heating

2: potassium carbonate / acetone / Reflux

With ammonium acetate; potassium carbonate; In ethanol; acetone; 1: |Mannich Aminomethylation / 1: |Mannich Aminomethylation;
DOI:10.1016/j.bmcl.2013.04.005