Fmoc-D-Allylglycine

Base Information

Chemical Name:Fmoc-D-Allylglycine
CAS No.:170642-28-1
Molecular Formula:C20H19NO4
Molecular Weight:337.375
Hs Code.:29242990
DSSTox Substance ID:DTXSID20427396
Nikkaji Number:J2.749.372F
Wikidata:Q72477742
Mol file:170642-28-1.mol

Synonyms:Fmoc-D-Allylglycine;170642-28-1;fmoc-d-gly(allyl)-oh;Fmoc-D-Allyglycine;(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid;Fmoc-D-allyl-Gly-OH;Fmoc-alpha-allyl-D-Gly;(2R)-2-(9H-fluoren-9-ylmethoxycarbonylamino)pent-4-enoic acid;fmoc-d-algly-oh;fmoc-(r)-2-amino-4-pentenoic acid;Fmoc--allyl-Gly-OH;Fmoc--allyl-D-Gly-OH;Fmoc-(R)-2-Allylglycine;(R)-2-Fmoc-amino-4-pentenoic acid;Fmoc-D-allylglycine;(S)-2-Fmoc-amino-4-pentenoic acid;Fmoc-L-allylglycine;SCHEMBL119527;DTXSID20427396;MFCD01311776;AKOS016843572;AC-9627;CS-W014495;HY-W013779;(R)-2-(Fmoc-amino)-4-pentenoic acid;PS-12150;Fmoc-D-allyl-Gly-OH, >=96.0% (HPLC);EN300-650362;F12314;Fmoc-|A inverted exclamation mark-allyl-D-Gly;N-FLUORENEMETHOXYCARBONYL-L-ALLYL GLYCINE;J-010638;(2R)-N-(9H-Fluorene-9-ylmethoxycarbonyl)-2-allylglycine;S-170642-28-1;(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-pentenoic acid;(R)-2-(((9H-fluoren-9-yl)methoxy)carbonylamino)pent-4-enoic acid;(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pent-4-enoic acid

Suppliers and Price of Fmoc-D-Allylglycine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-D-allylglycine
100mg
$ 305.00

TRC
Fmoc-D-allylglycine
500mg
$ 65.00

SynQuest Laboratories
D-2-Allylglycine, N-Fmoc protected 98%
5 g
$ 343.00

SynQuest Laboratories
D-2-Allylglycine, N-Fmoc protected 98%
10 g
$ 658.00

SynQuest Laboratories
D-2-Allylglycine, N-Fmoc protected 98%
1 g
$ 100.00

Sigma-Aldrich
Fmoc-D-allyl-Gly-OH ≥96.0% (HPLC)
250mg
$ 143.00

Matrix Scientific
Fmoc-D-allylglycine
1g
$ 37.00

Matrix Scientific
Fmoc-D-allylglycine
5g
$ 156.00

Matrix Scientific
Fmoc-D-allylglycine
25g
$ 581.00

Iris Biotech GmbH
Fmoc-D-AllylGly-OH
5 g
$ 330.75

Total 58 raw suppliers

Chemical Property of Fmoc-D-Allylglycine

Chemical Property:

Appearance/Colour:white granular powder
Vapor Pressure:1.64E-13mmHg at 25°C
Melting Point:134 °C
Refractive Index:1.5800 (estimate)
Boiling Point:563 °C at 760 mmHg
PKA:3.72±0.10(Predicted)
Flash Point:294.3 °C
PSA：66.84000
Density:1.245 g/cm³
LogP:3.50810
Storage Temp.:Store at 0°C
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:337.13140809
Heavy Atom Count:25
Complexity:484

Purity/Quality:

99%, ^*data from raw suppliers

Fmoc-D-allylglycine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Safety Statements: 24/25-22

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C=CCC(C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13
Isomeric SMILES:C=CC[C@H](C(=O)O)NC(=O)OCC1C2=CC=CC=C2C3=CC=CC=C13

Technology Process of Fmoc-D-Allylglycine

There total 2 articles about Fmoc-D-Allylglycine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 54594-06-8
D-allylglycine

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 170642-28-1
(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid

Guidance literature:: With triethylamine; In water; acetonitrile; for 2h;
DOI:10.1002/(SICI)1099-0690(199905)1999:5<1127::AID-EJOC1127>3.0.CO;2-A

Reference yield:

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 170642-23-6
(S,S)-pseudoephedrine D-allylglycinamide

: 90-82-4,7009-81-6,90-83-5,6912-63-6
pseudoephedrine

: 170642-28-1
(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid

Guidance literature:: With sodium hydroxide; sodium hydrogencarbonate; Yield given. Multistep reaction; 1.) reflux, 2.) 1.5 h;
DOI:10.1021/ja00137a034

Reference yield: 95.0%

: 35661-39-3,136132-75-7
N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

: C₂₀H₁₈NO₄Pol

: 132388-59-1
L-Asn(Trt)

: 146549-21-5
2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoic acid

: 170899-08-8
N-(tert-butoxycarbonyl)-D-allylglycine

: 170642-28-1
(R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid

: 936116-88-0
2-[2-(2-{2-[2-(2-tert-butoxycarbonylamino-pent-4-enoylamino)-propionylamino]-pent-4-enoylamino}-pent-4-enoylamino)-3-(trityl-carbamoyl)-propionylamino]-pent-4-enoic acid methyl ester

Guidance literature:: C₂₀H₁₈NO₄Pol; With piperidine; In 1-methyl-pyrrolidin-2-one; not specified

L-Asn(Trt); With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In 1-methyl-pyrrolidin-2-one; not specified

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine; 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoic acid; N-(tert-butoxycarbonyl)-D-allylglycine; (R)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)pent-4-enoic acid; Further stages;
DOI:10.1039/c3ob41359d