Benzoic acid, 2,4-difluoro-3-(triethylsilyl)-

Base Information

Chemical Name:Benzoic acid, 2,4-difluoro-3-(triethylsilyl)-
CAS No.:651027-06-4
Molecular Formula:C13H18F2O2Si
Molecular Weight:272.367
Hs Code.:
DSSTox Substance ID:DTXSID50464835
Wikidata:Q82290348

Synonyms:651027-06-4;2,4-DIFLUORO-3-(TRIETHYLSILYL)BENZOIC ACID;Benzoic acid, 2,4-difluoro-3-(triethylsilyl)-;DTXSID50464835

Suppliers and Price of Benzoic acid, 2,4-difluoro-3-(triethylsilyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzoic acid, 2,4-difluoro-3-(triethylsilyl)-

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:272.10441267
Heavy Atom Count:18
Complexity:287

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC[Si](CC)(CC)C1=C(C=CC(=C1F)C(=O)O)F

Technology Process of Benzoic acid, 2,4-difluoro-3-(triethylsilyl)-

There total 3 articles about Benzoic acid, 2,4-difluoro-3-(triethylsilyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 124-38-9,18923-20-1
carbon dioxide

: 651027-02-0
1-triethylsilyl-2,6-difluorobenzene

: 651027-06-4
2,4-difluoro-3-(triethylsilyl)benzoic acid

Guidance literature:: With sec.-butyllithium; In tetrahydrofuran; cyclohexane; for 0.75h;
DOI:10.1002/ejoc.200300354

Reference yield:

: 372-18-9
1,3-Difluorobenzene

: 651027-06-4
2,4-difluoro-3-(triethylsilyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / butyllithium / hexane; tetrahydrofuran / -75 °C

2: 89 percent / sec-butyllithium / cyclohexane; tetrahydrofuran / 0.75 h

With n-butyllithium; sec.-butyllithium; In tetrahydrofuran; hexane; cyclohexane;
DOI:10.1002/ejoc.200300354

Reference yield:

: 994-30-9
triethylsilyl chloride

: 651027-06-4
2,4-difluoro-3-(triethylsilyl)benzoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / butyllithium / hexane; tetrahydrofuran / -75 °C

2: 89 percent / sec-butyllithium / cyclohexane; tetrahydrofuran / 0.75 h

With n-butyllithium; sec.-butyllithium; In tetrahydrofuran; hexane; cyclohexane;
DOI:10.1002/ejoc.200300354