3,4-DIMETHYLTHIOANISOLE

Base Information

• Chemical Name: 3,4-DIMETHYLTHIOANISOLE
• CAS No.: 65398-69-8
• Molecular Formula: C9H12S
• Molecular Weight: 152.26
• Hs Code.: 2930909090
• Mol file: 65398-69-8.mol

Synonyms:3,4-Dimethyl-phenylisothiocyanat;3,4-dimethylphenyl methyl sulfide;3,4-dimethylphenyl-isothiocyanate;3,4-dimethylbenzenisothiocyanate;<3,4-Dimethyl-phenyl>-methyl-sulfid;4-isothiocyanato-1,2-dimethyl-benzene;3,4-Xylyl isothiocyanate;

Chemical Property of 3,4-DIMETHYLTHIOANISOLE

Chemical Property:

• PSA: 25.30000
• LogP: 3.02530

Purity/Quality:

99% ^*data from raw suppliers

3,4-Dimethylthioanisole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,4-DIMETHYLTHIOANISOLE

There total 5 articles about 3,4-DIMETHYLTHIOANISOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

4,4-dimethylcyclohexa-2,5-dienone (1073-14-9) + Trimethyl(methylthio)silane (3908-55-2) → 1,2-Dimethyl-4-(methylthio)benzene (65398-69-8)

Guidance literature:

With trifluorormethanesulfonic acid; In dichloromethane; for 12h; Reflux;

DOI:10.1039/b915294f

Reference yield:

p-fluorothioanisole (371-15-3) + methyl iodide (74-88-4) → 4-methylphenyl methylsulfide (623-13-2) + 1,2-Dimethyl-4-(methylthio)benzene (65398-69-8) + 1-(Ethylthio)-4-fluorobenzene (2924-75-6) + 1-fluoro-2-methyl-4-methylsulfanyl-benzene (252555-29-6)

Guidance literature:

p-fluorothioanisole; With n-butyllithium; In tetrahydrofuran; hexane; at -50 ℃; for 6h;

methyl iodide; In tetrahydrofuran; hexane; at 20 ℃; for 3h; Title compound not separated from byproducts;

DOI:10.1016/S0022-1139(99)00097-4

Reference yield:

3,4-dimethylthiophenol (18800-53-8) → 1,2-Dimethyl-4-(methylthio)benzene (65398-69-8)

Guidance literature:

With triethylamine; In acetone;

upstream raw materials:

3,4-dimethylthiophenol

dimethyl sulfate

p-fluorothioanisole

methyl iodide

Downstream raw materials:

Thiocarbonic acid S-(4,5-dimethyl-2-methylsulfanyl-phenyl) ester O-methyl ester

1,2-dimethyl-4-(methylsulfinyl)benzene

methylene chloride

3,4-dimethylthiophenol