2-(2-Fluorophenyl)-4,4-dimethyl-2-oxazoline

Base Information

Chemical Name:2-(2-Fluorophenyl)-4,4-dimethyl-2-oxazoline
CAS No.:66464-20-8
Molecular Formula:C11H12FNO
Molecular Weight:193.221
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00447214
Nikkaji Number:J1.285.639C

Synonyms:66464-20-8;2-(2-fluorophenyl)-4,4-dimethyl-2-oxazoline;2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole;2-(2-fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole;2-(2-fluorophenyl)-4,4-dimethyl-5H-1,3-oxazole;MFCD04108264;2-(2-FLUOROPHENYL)-4,5-DIHYDRO-4,4-DIMETHYLOXAZOLE;SCHEMBL7223905;DTXSID00447214;OZOYGQPOXFKXHD-UHFFFAOYSA-N;AB3813;AKOS005068046;CS-0454707;A923598

Suppliers and Price of 2-(2-Fluorophenyl)-4,4-dimethyl-2-oxazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(2-Fluorophenyl)-4,5-dihydro-4,4-dimethyloxazole
50mg
$ 90.00

Crysdot
2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole 95+%
5g
$ 792.00

Apolloscientific
2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 95%
250mg
$ 235.00

Apolloscientific
2-(2-Fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole 95%
1g
$ 595.00

AK Scientific
2-(2-Fluorophenyl)-4,5-dihydro-4,4-dimethyloxazole
250mg
$ 304.00

Total 3 raw suppliers

Chemical Property of 2-(2-Fluorophenyl)-4,4-dimethyl-2-oxazoline

Chemical Property:

PSA：21.59000
LogP:1.81670
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:193.090292168
Heavy Atom Count:14
Complexity:250

Purity/Quality:

97% ^*data from raw suppliers

2-(2-Fluorophenyl)-4,5-dihydro-4,4-dimethyloxazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1(COC(=N1)C2=CC=CC=C2F)C

Technology Process of 2-(2-Fluorophenyl)-4,4-dimethyl-2-oxazoline

There total 18 articles about 2-(2-Fluorophenyl)-4,4-dimethyl-2-oxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 179116-95-1
N-(2-chloro-1,1-dimethyl-ethyl)-2-fluoro-benzamide

: 66464-20-8
2-(2-fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

Guidance literature:: With sodium hydroxide; In methanol; for 3h; Heating;
DOI:10.1016/0040-4020(96)00267-0

Reference yield: 95.0%

: 124-68-5
2-Amino-2-methyl-1-propanol

: 446-52-6
2-Fluorobenzaldehyde

: 66464-20-8
2-(2-fluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole

Guidance literature:: 2-Amino-2-methyl-1-propanol; 2-Fluorobenzaldehyde; In dichloromethane; at 25 ℃; for 20h; Inert atmosphere; Schlenk technique; Molecular sieve;

With N-Bromosuccinimide; In dichloromethane; at 25 ℃; for 4h; Inert atmosphere; Schlenk technique; Molecular sieve;
DOI:10.1021/acs.orglett.9b01350