4-(3-(3,4-Dimethoxyphenoxy)-3-phenylpropyl)morpholine

Base Information

Chemical Name:4-(3-(3,4-Dimethoxyphenoxy)-3-phenylpropyl)morpholine
CAS No.:157846-75-8
Molecular Formula:C₂₁H₂₇NO₄
Molecular Weight:357.45
Hs Code.:
DSSTox Substance ID:DTXSID10935819

Synonyms:4-(3-(3,4-Dimethoxyphenoxy)-3-phenylpropyl)morpholine;Morpholine, 4-(3-(3,4-dimethoxyphenoxy)-3-phenylpropyl)-;157846-75-8;4-[3-(3,4-dimethoxyphenoxy)-3-phenylpropyl]morpholine;DTXSID10935819;LS-92738

Suppliers and Price of 4-(3-(3,4-Dimethoxyphenoxy)-3-phenylpropyl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 4-(3-(3,4-Dimethoxyphenoxy)-3-phenylpropyl)morpholine

Chemical Property:

Vapor Pressure:1.91E-10mmHg at 25°C
Boiling Point:508.1°C at 760 mmHg
Flash Point:145.6°C
PSA：40.16000
Density:1.115g/cm³
LogP:3.48410
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:8
Exact Mass:357.19400834
Heavy Atom Count:26
Complexity:382

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=C(C=C1)OC(CCN2CCOCC2)C3=CC=CC=C3)OC

Technology Process of 4-(3-(3,4-Dimethoxyphenoxy)-3-phenylpropyl)morpholine

There total 4 articles about 4-(3-(3,4-Dimethoxyphenoxy)-3-phenylpropyl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2298-48-8
3-morpholin-4-yl-1-phenyl-propan-1-one

: 157846-75-8
4-[3-(3,4-Dimethoxy-phenoxy)-3-phenyl-propyl]-morpholine

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / NaBH₄ / methanol

2: 59 percent / K₂CO₃ / acetone / 24 h / 0 - 4 °C

3: 1.) NaOH / 1.) aq. EtOH, 32 deg C, 10 min, 2.) aq. EtOH, 32 deg C, 48 h

With sodium hydroxide; sodium tetrahydroborate; potassium carbonate; In methanol; acetone;

Reference yield:

: 4441-34-3
3-morpholino-1-phenylpropan-1-ol

: 157846-75-8
4-[3-(3,4-Dimethoxy-phenoxy)-3-phenyl-propyl]-morpholine

Guidance literature:: Multi-step reaction with 2 steps

1: 59 percent / K₂CO₃ / acetone / 24 h / 0 - 4 °C

2: 1.) NaOH / 1.) aq. EtOH, 32 deg C, 10 min, 2.) aq. EtOH, 32 deg C, 48 h

With sodium hydroxide; potassium carbonate; In acetone;

Reference yield:

: 98-86-2
acetophenone

: 157846-75-8
4-[3-(3,4-Dimethoxy-phenoxy)-3-phenyl-propyl]-morpholine

Guidance literature:: Multi-step reaction with 4 steps

1: 75 percent / conc. HCl / ethanol / 6 h / Heating

2: 80 percent / NaBH₄ / methanol

3: 59 percent / K₂CO₃ / acetone / 24 h / 0 - 4 °C

4: 1.) NaOH / 1.) aq. EtOH, 32 deg C, 10 min, 2.) aq. EtOH, 32 deg C, 48 h

With hydrogenchloride; sodium hydroxide; sodium tetrahydroborate; potassium carbonate; In methanol; ethanol; acetone;