Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-

Base Information

Chemical Name:Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-
CAS No.:680610-54-2
Molecular Formula:C10H9F4NO2
Molecular Weight:251.181
Hs Code.:
DSSTox Substance ID:DTXSID50458416
Wikidata:Q82281678

Synonyms:680610-54-2;2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)benzamide;Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-;SCHEMBL1125455;2-Fluoro-N-methoxy-N-methyl-3-trifluoromethyl-benzamide;DTXSID50458416;AKOS018444004;2-fluoro-3-trifluoromethyl-N-methoxy-N-methylbenzamide;2-fluoro-N-methoxy-N-methyl-3-trifluoromethylbenzamide;2- fluoro-3-trifluoromethyl-N-methoxy-N-methylbenzamide

Suppliers and Price of Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:251.05694118
Heavy Atom Count:17
Complexity:282

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C(=O)C1=C(C(=CC=C1)C(F)(F)F)F)OC

Technology Process of Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)-

There total 5 articles about Benzamide, 2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 208173-19-7
2-fluoro-3-trifluoromethylbenzoyl chloride

: 680610-54-2
2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)benzamide

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 24h;

Reference yield:

: 115029-22-6
2-fluoro-3-(trifluoromethyl)benzoic acid

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 680610-54-2
2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)benzamide

Guidance literature:: With pyridine; oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃;

Reference yield:

: 115029-22-6
2-fluoro-3-(trifluoromethyl)benzoic acid

: 680610-54-2
2-fluoro-N-methoxy-N-methyl-3-(trifluoromethyl)benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: 4-methyl-morpholine / tetrahydrofuran / 1 h / 20 °C

2: 8 h / 20 °C

With 4-methyl-morpholine; In tetrahydrofuran;
DOI:10.1021/tx100045h