N-methyl-4-ethoxycarbonylmethylaniline

Base Information

Chemical Name:N-methyl-4-ethoxycarbonylmethylaniline
CAS No.:68787-97-3
Molecular Formula:C11H15NO2
Molecular Weight:193.246
Hs Code.:
DSSTox Substance ID:DTXSID50468398
Nikkaji Number:J31.467F
Wikidata:Q82295574

Synonyms:(4-methylaminophenyl)-acetic acid ethyl ester;N-methyl-4-ethoxycarbonylmethylaniline;68787-97-3;SCHEMBL2636023;DTXSID50468398;XUMSFHJEGJGJEQ-UHFFFAOYSA-N;ethyl [4-(methylamino)phenyl]acetate;(4-Methylamino-phenyl)-acetic acid ethyl ester

Suppliers and Price of N-methyl-4-ethoxycarbonylmethylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-methyl-4-ethoxycarbonylmethylaniline

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:193.110278721
Heavy Atom Count:14
Complexity:174

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=CC=C(C=C1)NC

Technology Process of N-methyl-4-ethoxycarbonylmethylaniline

There total 7 articles about N-methyl-4-ethoxycarbonylmethylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5438-70-0
ethyl (4-amino-3,5-dibromophenyl)acetate

: 74-88-4
methyl iodide

: 68787-97-3
N-methyl-4-ethoxycarbonylmethylaniline

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In toluene; at 90 ℃; for 18h;
DOI:10.1016/j.ejmech.2014.01.048

Reference yield:

: 5438-70-0
ethyl (4-amino-3,5-dibromophenyl)acetate

: 68787-97-3
N-methyl-4-ethoxycarbonylmethylaniline

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / CH₂Cl₂ / 1 h / Ambient temperature

2: K₂CO₃ / dimethylformamide / 3 h / Ambient temperature

3: metallic sodium/abs. ethanol / 0.5 h / Ambient temperature

With ethanol; sodium; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1248/cpb.31.3424

Reference yield:

: 88975-34-2
ethyl 4-<(trifluoroacetyl)amino>benzeneacetate

: 68787-97-3
N-methyl-4-ethoxycarbonylmethylaniline

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 3 h / Ambient temperature

2: metallic sodium/abs. ethanol / 0.5 h / Ambient temperature

With ethanol; sodium; potassium carbonate; In N,N-dimethyl-formamide;
DOI:10.1248/cpb.31.3424