10-Undecenophenone

Base Information

• Chemical Name: 10-Undecenophenone
• CAS No.: 7028-27-5
• Molecular Formula: C17H24O
• Molecular Weight: 244.377
• DSSTox Substance ID: DTXSID001311896
• Mol file: 7028-27-5.mol

Synonyms:10-undecenophenone;1-Phenyl-10-undecen-1-one;DTXSID001311896;7028-27-5

Chemical Property of 10-Undecenophenone

Chemical Property:

• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 10
• Exact Mass: 244.182715385
• Heavy Atom Count: 18
• Complexity: 226

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C=CCCCCCCCCC(=O)C1=CC=CC=C1

Technology Process of 10-Undecenophenone

There total 7 articles about 10-Undecenophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N-methyl-N-methoxyundec-10-enamide (102613-04-7) + phenylmagnesium bromide (100-58-3) → 1-phenylundec-10-en-1-one (7028-27-5)

Guidance literature:

In tetrahydrofuran; diethyl ether; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/acs.orglett.6b02743

Reference yield: 80.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + undec-10-enoyl chloride (38460-95-6) → 1-phenylundec-10-en-1-one (7028-27-5) + phenyl 2-decenyl ketone + 10-undecenoic acid 4-chlorobutyl ester

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; phenylmagnesium bromide; at 0 ℃;

DOI:10.1016/0040-4039(95)01936-C

Reference yield: 5.0%

undec-10-enoyl chloride (38460-95-6) + phenylmagnesium bromide (100-58-3) → 1-phenylundec-10-en-1-one (7028-27-5) + phenyl 2-decenyl ketone + 10-undecenoic acid 4-chlorobutyl ester

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; at 0 ℃;

DOI:10.1016/0040-4039(95)01936-C

upstream raw materials:

undec-10-enoyl chloride

diphenyl cadmium

tetrahydrofuran

phenylmagnesium bromide

Downstream raw materials:

2-Methyl-13-oxo-13-phenyl-tridecanoic acid