Cyclohexyl methyl methylphosphonate

Base Information

• Chemical Name: Cyclohexyl methyl methylphosphonate
• CAS No.: 7040-52-0
• Molecular Formula: C₈H₁₇O₃P
• Molecular Weight: 192.195
• Mol file: 7040-52-0.mol

Synonyms:Methylphosphonsaeuremethylcyclohexylester;Methylphosphonsaeure-cyclohexylester-methylester;cyclohexyl methyl methylphosphonate;Phosphonic acid,methyl-,cyclohexyl methyl ester;

Chemical Property of Cyclohexyl methyl methylphosphonate

Chemical Property:

• Vapor Pressure: 0.0201mmHg at 25°C
• Boiling Point: 260.2oC at 760 mmHg
• Flash Point: 125.2oC
• PSA: 45.34000
• Density: 1.05g/cm3
• LogP: 2.80500
• Water Solubility.: It is sparingly soluble in both organic solvents and water, but become more soluble in water when neutralized to phosphonates at

Purity/Quality:

99% ^*data from raw suppliers

CYCLOHEXYL METHYL METHYLPHOSPHONATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Cyclohexyl methyl methylphosphonate or phosphonic acid is used as a micro-nano electronic materials have extended self-assembled monolayers (SAMs) beyond conventional gold/thiol systems. To expand the choice of the substrate used for the preparation of SAMs, the chemical functionalities in film-forming molecules can be altered by introducing phosphate or phosphonate groups. Such polar acidic molecules are capable of interacting with diverse metal-oxide surfaces (e.g., Al2O3, Ta2O5, NbO5, ZrO2 and TiO2) and form films with a similar degree of ordering as for alkyl thiol SAMs on gold.

Technology Process of Cyclohexyl methyl methylphosphonate

There total 8 articles about Cyclohexyl methyl methylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

Phosphorous acid cyclohexyl ester dimethyl ester (175352-88-2) + methyl iodide (74-88-4) → cyclohexyl methyl methylphosphonate (7040-52-0)

Guidance literature:

for 2h; Heating;

DOI:10.1039/b007077g

Reference yield: 31.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + methylphosphonic acid dichloroanhydride (676-97-1) + cyclohexanol (108-93-0) → cyclohexyl methyl methylphosphonate (7040-52-0)

Guidance literature:

methylphosphonic acid dichloroanhydride; cyclohexanol; In toluene; at 105 ℃; for 2h;

With water; at 105 ℃; for 2h;

diazomethane; for 0.166667h; Heating;

DOI:10.1080/104265090889602

Reference yield:

methylphosphonic acid monocyclohexyl ester (1932-60-1) + diazomethyl-trimethyl-silane (18107-18-1) → cyclohexyl methyl methylphosphonate (7040-52-0)

Guidance literature:

With methanol; In tetrahydrofuran; benzene; at 20 ℃;

DOI:10.1080/10426500490459632

upstream raw materials:

methyl methylphosphonochloridate

sodium cyclohexanolate

methanol

GF

Downstream raw materials:

methylphosphonic acid monocyclohexyl ester

Refernces

• 1、 Crenshaw, Michael D.,Cummings, David B.. "Preparation, derivatization with trimethylsilyldiazomethane, and GC/MS analysis of a "pool" of alkyl methylphosphonic acids for use as qualitative standards in support of counterterrorism and the chemical weapons convention". . p. 1009 - 1018. Retrieved 2007/10/03.
• 2、 Timperley, Christopher M.,Bird, Michael,Holden, Ian,Black, Robin M.. "Organophosphorus chemistry. Part 1: The synthesis of alkyl methylphosphonic acids". . p. 26 - 30. Retrieved 2007/10/03.