5-(Methoxymethyl)quinolin-8-ol

Base Information

Chemical Name:5-(Methoxymethyl)quinolin-8-ol
CAS No.:7545-59-7
Molecular Formula:C11H11NO2
Molecular Weight:189.21100
Hs Code.:
DSSTox Substance ID:DTXSID90351078
Nikkaji Number:J460.829A
Wikidata:Q82127191
ChEMBL ID:CHEMBL1518735
Mol file:7545-59-7.mol

Synonyms:5-(methoxymethyl)quinolin-8-ol;7545-59-7;5-Methoxymethyl-quinolin-8-ol;MLS000067656;Oprea1_538594;5-methyloxymethyl-8-quinolinol;SCHEMBL4468901;CHEMBL1518735;DTXSID90351078;YNADRYIGLPRUCC-UHFFFAOYSA-N;5-methoxymethyl-8-hydroxyquinoline;HMS2156O20;HMS3353P13;MFCD00226929;STK029159;AKOS004119282;SB68064;5-(METHOXYMETHYL)-8-QUINOLINOL;LS-08553;SMR000125080;SR-01000389094;SR-01000389094-1

Suppliers and Price of 5-(Methoxymethyl)quinolin-8-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
5-(Methoxymethyl)quinolin-8-ol 95+%
1g
$ 673.00

Chemenu
5-(Methoxymethyl)quinolin-8-ol 95%
1g
$ 636.00

Total 7 raw suppliers

Chemical Property of 5-(Methoxymethyl)quinolin-8-ol

Chemical Property:

PSA：42.35000
LogP:2.08680
XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:189.078978594
Heavy Atom Count:14
Complexity:186

Purity/Quality:

99% ^*data from raw suppliers

5-(Methoxymethyl)quinolin-8-ol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCC1=C2C=CC=NC2=C(C=C1)O

Technology Process of 5-(Methoxymethyl)quinolin-8-ol

There total 6 articles about 5-(Methoxymethyl)quinolin-8-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 67-56-1
methanol

: 4053-45-6
5-chloromethyl-8-hydroxyquinoline hydrochloride

: 7545-59-7
5-(Methoxymethyl)-8-hydroxychinolin

Guidance literature:: With sodium hydrogencarbonate; Heating;

Reference yield: 20.0%

: 124-41-4
sodium methylate

: 4053-45-6
5-chloromethyl-8-hydroxyquinoline hydrochloride

: 7545-59-7
5-(Methoxymethyl)-8-hydroxychinolin

Guidance literature:: In methanol; at 20 ℃; for 4h;

Reference yield:

: 148-24-3,24804-14-6
8-quinolinol

: 7545-59-7
5-(Methoxymethyl)-8-hydroxychinolin

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / 12 h / 20 °C

2: sodium hydrogencarbonate / 2 h / Reflux

With hydrogenchloride; sodium hydrogencarbonate;
DOI:10.1039/c8cp03226b