2-Propanone, 1-methoxy-1-phenyl-

Base Information

• Chemical Name: 2-Propanone, 1-methoxy-1-phenyl-
• CAS No.: 7624-24-0
• Molecular Formula: C10H12O2
• Molecular Weight: 164.204
• DSSTox Substance ID: DTXSID00404281
• Nikkaji Number: J324.843G
• Mol file: 7624-24-0.mol

Synonyms:1-Methoxy-1-phenyl-aceton;1-methoxy-1-phenyl-2-propanone;2-Propanone,1-methoxy-1-phenyl;1-methoxy-1-phenyl-propan-2-one;

Chemical Property of 2-Propanone, 1-methoxy-1-phenyl-

Chemical Property:

• Melting Point: 107-109 °C
• Boiling Point: 107-108 °C(Press: 15 Torr)
• PSA: 26.30000
• Density: 1.029±0.06 g/cm3(Predicted)
• LogP: 1.96310
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 164.083729621
• Heavy Atom Count: 12
• Complexity: 148

Purity/Quality:

1-methoxy-1-phenylpropan-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)C(C1=CC=CC=C1)OC

Technology Process of 2-Propanone, 1-methoxy-1-phenyl-

There total 53 articles about 2-Propanone, 1-methoxy-1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-Methoxy-2-oximino-1-phenyl-propan (21165-25-3) → 1-methoxy-1-phenyl-acetone (7624-24-0)

Guidance literature:

With hydrogenchloride; levulinic acid; at 80 ℃; for 3.5h;

Reference yield: 88.0%

2-Hydroxypropiophenone dimethylacetal (73611-99-1) → 1-methoxy-1-phenyl-acetone (7624-24-0)

Guidance literature:

With iodine; triphenylphosphine; In benzene; for 15h; Ambient temperature;

DOI:10.1016/S0040-4020(01)86104-4

Reference yield: 76.0%

1,1-dimethoxy-2-phenylcyclopropane (18523-34-7) → 1-methoxy-1-phenyl-acetone (7624-24-0)

Guidance literature:

With trifluoroacetic acid; In nitromethane; at 60 ℃; for 4h;

upstream raw materials:

methanol

1-bromo-1-phenyl-2-propanone

2-methyl-1-methoxy-1-phenyl-oxirane

diethyl ether

Downstream raw materials:

(1RS,2RS)-1-methoxy-1,2-diphenyl-propan-2-ol

benzoic acid methyl ester

benzaldehyde

syn-1-methoxy-1-phenyl-2-propanol