18523-34-7

Upstream product

• 100-42-5 styrene 
• 1155-77-7 1,2,3,4-tetrachloro-5-phenyl-7,7-dimethoxybicyclo<2.2.1>hepta-2,5-diene 
• 67-56-1 methanol 
• 2415-80-7 1,1-dichloro-2-phenylcyclopropane 
• 70372-58-6 2-bromo-2-fluoro-1-phenylcyclopropane 
• 3234-51-3 1,1-dibromo-2-phenylcyclopropane 
• 124-41-4 sodium methylate 
• 108-98-5 thiophenol 
• 67-63-0 isopropyl alcohol 

Downstream Products

• 57260-85-2 2,2,3,3-tetracyano-1,1-dimethoxy-4-phenyl-cyclopentane 
• 2021-28-5 ethyl dihydrocinnamate 
• 21165-34-4 1-ethoxy-1-phenyl-2-propanone 
• 39228-29-0 (E)-methyl 2-nitrocinnamate 
• 637-57-0 p-nitrocinnamic acid methyl ester 
• 90104-62-4 methyl 3-(acetyloxy)-3-phenylpropanoate 
• 103-26-4 Methyl cinnamate 
• 7624-24-0 1-methoxy-1-phenyl-acetone 
• 103-26-4 methyl cinnamate 
• 103-25-3 3-phenylpropanoic acid methyl ester 
• 3967-53-1 methyl tropate 
• 31508-44-8 2-phenylpropionic acid methyl ester 

Relevant academic research and scientific papers

Reduction and carbonylation of gem-dihalogeno cyclopropanes with iron pentacarbonyl

Reductive carbonylation of a gem-dibromo cyclopropane to carbomethoxycyclopropane can be achieved with excess Fe(CO)5 in DMF and an added nucleophile such as MeOH or MeONa.

Reactions of gem-Dihalophenylcyclopropanes with Nucleophilic Agents: Formation of Phenylcyclopropanone and 2-Phenylpropenal Acetals

Reactions of gem-dihalophenylcyclopropanes with alcohols in dimethyl sulfoxide in the presence of potassium tert-butoxide yield phenylcyclopropanone acetals. Reactions with alcohols in the presence of potassium hydroxide at 80-100°C yield cyclopropanone and 2-phenylpropenal acetals; their ratio depends mostly on the nature of the nucleophile.

Reductive Carbonylation of gem-Dihalogenocyclopropanes by Pentacarbonyliron(0) in the Presence of Sodium Methoxide

The reaction of gem-dihalogenocyclopropanes derivatives with (tetracarbonyl)(methoxycarbonylato)ferrate(I-) has been investigated; gem-dibromocyclopropanes and gem-chlorobromocyclopropane derivatives are reduced and carbonylated.It could be shown that a bromo ester such as methyl 1-bromo-2-phenylcyclopropanecarboxylate is an intermediate in the transformation of 1,1-dibromo-2-phenylcyclopropane into methyl cis- and trans-2-phenylcyclopropanecarboxylates and dimethyl 2-phenyl-1,1-cyclopropanedicarboxylate.

SYNTHESIS OF MIXED ACETALS OF CYCLOPROPANONE. INVESTIGATION OF THEIR STABILITY AND THE MECHANISM OF OPENING OF THE CYCLOPROPANE RING

A series of mixed O,O- and O,S-acetals of arylcyclopropanone were synthesized by the reaction of 1,1-dihalogeno-2-arylcyclopropanes with nucleophilic agents of basic type, and their stability was studied in relation to the polar effect of the substituents