4-Hydroxy-4-(pyridin-2-yl)butan-2-one

Base Information

Chemical Name:4-Hydroxy-4-(pyridin-2-yl)butan-2-one
CAS No.:6337-41-3
Molecular Formula:C9H11NO2
Molecular Weight:165.192
Hs Code.:
NSC Number:38034
DSSTox Substance ID:DTXSID70284618
Nikkaji Number:J2.174.236H
Mol file:6337-41-3.mol

Synonyms:4-hydroxy-4-(pyridin-2-yl)butan-2-one;6337-41-3;4-Hydroxy-4-pyridin-2-yl-butan-2-one;4-hydroxy-4-pyridin-2-ylbutan-2-one;NSC38034;DTXSID70284618;BBL028836;NSC-38034;STL372745;AKOS000583154;AKOS024269440;VS-08991;CS-0322759;EU-0051243;4-HYDROXY-4-(2-PYRIDYL)-2-BUTANONE

Suppliers and Price of 4-Hydroxy-4-(pyridin-2-yl)butan-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-HYDROXY-4-(2-PYRIDINYL)-2-BUTANONE 95.00%
5MG
$ 503.72

aablocks
4-hydroxy-4-pyridin-2-yl-butan-2-one
5g
$ 2057.00

aablocks
4-hydroxy-4-pyridin-2-yl-butan-2-one
500mg
$ 529.00

Total 5 raw suppliers

Chemical Property of 4-Hydroxy-4-(pyridin-2-yl)butan-2-one

Chemical Property:

Vapor Pressure:0.000511mmHg at 25°C
Boiling Point:300.1°Cat760mmHg
Flash Point:135.3°C
PSA：50.19000
Density:1.148g/cm³
LogP:1.09410
XLogP3:-0.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:165.078978594
Heavy Atom Count:12
Complexity:159

Purity/Quality:: 4-HYDROXY-4-(2-PYRIDINYL)-2-BUTANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)CC(C1=CC=CC=N1)O

Technology Process of 4-Hydroxy-4-(pyridin-2-yl)butan-2-one

There total 12 articles about 4-Hydroxy-4-(pyridin-2-yl)butan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1121-60-4
pyridine-2-carbaldehyde

: 67-64-1
acetone

: 6337-41-3
4-hydroxy-4-(pyridin-2-yl)butan-2-one

Guidance literature:: With pyrrolidine; In water; for 0.0833333h; pH=11.75;
DOI:10.1016/j.tet.2005.03.045

Reference yield: 79.0%

: 1121-60-4
pyridine-2-carbaldehyde

: 14035-54-2
1,1-diphenyl-1-hydroxy-3-butanone

: 6337-41-3
4-hydroxy-4-(pyridin-2-yl)butan-2-one

Guidance literature:: pyridine-2-carbaldehyde; 1,1-diphenyl-1-hydroxy-3-butanone; With trimethylaluminum; 1,1'-bi-2-naphthol; In dichloromethane; at 20 ℃; for 43h;

With hydrogenchloride; In dichloromethane;
DOI:10.1016/j.tetlet.2006.08.003

Reference yield: 74.0%

: 1121-60-4
pyridine-2-carbaldehyde

: 123-42-2
4-Hydroxy-4-methyl-2-pentanone

: 6337-41-3
4-hydroxy-4-(pyridin-2-yl)butan-2-one

Guidance literature:: With trimethylaluminum; 1,1'-bi-2-naphthol; In dichloromethane; toluene; at 20 ℃; for 43h;
DOI:10.1016/j.tetlet.2006.02.044