(cis)-4-PPC

Base Information

Chemical Name:(cis)-4-PPC
CAS No.:78165-06-7
Molecular Formula:C17H25NO
Molecular Weight:259.392
Hs Code.:
Mol file:78165-06-7.mol

Synonyms:4-phenyl-4-piperidinocyclohexanol;4-phenyl-4-(1-piperidinyl)cyclohexanol;RAC CIS-4-PHENYL-4-(1-PIPERIDINYL)CYCLOHEXANOL;

Suppliers and Price of (cis)-4-PPC

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (cis)-4-PPC

Chemical Property:

PSA：23.47000
LogP:3.24060

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses cis-4-Phenyl-4-(1-piperidinyl)cyclohexanol is the cis-isomer of the 4-hydroxy(cyclo) metabolite of Phencyclidine (P295502). cis-4-Phenyl-4-(1-piperidinyl)cyclohexanol is the less active of the two isomer and its activity is insignificant compared to PCP itself.

Technology Process of (cis)-4-PPC

There total 6 articles about (cis)-4-PPC which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 956-90-1
phencyclidine hydrochloride

: 60232-85-1
1-(1-phenylcyclohexyl)-4-hydroxypiperidine

: 78165-06-7
r-4-phenyl-4-(1-piperidinyl)-t-cyclohexanol

: 78165-07-8
r-4-phenyl-4-(1-piperidinyl)-c-cyclohexanol

Guidance literature:: In water; Ambient temperature; Cunninghamella echinulata; metabolism by microorganisms; further microbial agents;
DOI:10.1002/jps.2600700210

Reference yield:

: 13482-22-9
4-hydroxycyclohexanone

: 78165-06-7
r-4-phenyl-4-(1-piperidinyl)-t-cyclohexanol

Guidance literature:: Multi-step reaction with 4 steps

1: 5.1 g

2: NaN₃, CCl₃COOH / CHCl₃ / 5 h / 0 °C

3: LiAlH₄ / diethyl ether / Heating

4: 0.8 g / K₂CO₃ / acetone / 96 h / Heating

With lithium aluminium tetrahydride; sodium azide; potassium carbonate; trichloroacetic acid; In diethyl ether; chloroform; acetone;
DOI:10.1021/jm00346a019

Reference yield:

: phenylmagnesium bromide

: 78165-06-7
r-4-phenyl-4-(1-piperidinyl)-t-cyclohexanol

Guidance literature:: Multi-step reaction with 4 steps

1: 5.1 g

2: NaN₃, CCl₃COOH / CHCl₃ / 5 h / 0 °C

3: LiAlH₄ / diethyl ether / Heating

4: 0.8 g / K₂CO₃ / acetone / 96 h / Heating

With lithium aluminium tetrahydride; sodium azide; potassium carbonate; trichloroacetic acid; In diethyl ether; chloroform; acetone;
DOI:10.1021/jm00346a019