(2-AMINO-5-CHLOROPHENYL)(4-FLUOROPHENYL)METHANONE

Base Information

• Chemical Name: (2-AMINO-5-CHLOROPHENYL)(4-FLUOROPHENYL)METHANONE
• CAS No.: 784-40-7
• Molecular Formula: C13H9ClFNO
• Molecular Weight: 249.672
• Hs Code.: 2922399090
• Mol file: 784-40-7.mol

Synonyms:2-Amino-5-chlor-4'-fluorbenzophenon;F2102-0108;4-chloro-2-(4-fluorobenzoyl)aniline;(2-amino-5-chlorophenyl)(4-fluorophenyl)methanone;

Chemical Property of (2-AMINO-5-CHLOROPHENYL)(4-FLUOROPHENYL)METHANONE

Chemical Property:

• PSA: 43.09000
• LogP: 3.87350

Purity/Quality:

99% ^*data from raw suppliers

(2-AMINO-5-CHLORO-PHENYL)-(4-FLUORO-PHENYL)METHANONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2-AMINO-5-CHLOROPHENYL)(4-FLUOROPHENYL)METHANONE

There total 7 articles about (2-AMINO-5-CHLOROPHENYL)(4-FLUOROPHENYL)METHANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.4%

2-amino-5-chlorobenzonitrile (5922-60-1) + 4-flourophenylmagnesium bromide (352-13-6) → (2-amino-5-chlorophenyl)(4-fluorophenyl)methanone (784-40-7)

Guidance literature:

In tetrahydrofuran; at 0 - 20 ℃; Cooling with ice;

Reference yield: 76.0%

N-[4-chloro-2-(4-fluoro-benzoyl)-phenyl]-4-fluoro-benzamide (869365-90-2) → (2-amino-5-chlorophenyl)(4-fluorophenyl)methanone (784-40-7)

Guidance literature:

N-[4-chloro-2-(4-fluoro-benzoyl)-phenyl]-4-fluoro-benzamide; With water; acetic acid; hydrogenchloride; at 105 ℃; for 16h;

With sodium hydroxide; In dichloromethane; water;

Reference yield:

4-fluorobenzoyl chloride (403-43-0) + 4-chloro-aniline (106-47-8) → (2-amino-5-chlorophenyl)(4-fluorophenyl)methanone (784-40-7)

Guidance literature:

With zinc(II) chloride; at 200 - 230 ℃; for 3h;

DOI:10.1002/jhet.5570380320

upstream raw materials:

N-(2-(4-fluorobenzoyl)-4-chlorophenyl)acetamide

4-fluorobenzoyl chloride

4-chloro-aniline

6-chloro-2-methyl-4H-benzo[d][1,3]oxazin-4-one

Downstream raw materials:

(2-amino-5-chloro-phenyl)-(4-fluoro-phenyl)-methanol

<(S)->2-amino-5-chloro-4'-fluorobenzhydrol

2-Bromacetylamino-5-chlor-4'-fluor-benzophenon

7-chloro-5-(p-fluorophenyl)-3H-[1,4]benzodiazepin-2-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 784-40-7 (2-AMINO-5-CHLOROPHENYL)(4-FLUOROPHENYL)METHANONE

Send

Send

Metric Ton KG G Pound L ML

Send

Send