Propane, 2-methyl-2-(2,2,2-trifluoroethoxy)-

Base Information

• Chemical Name: Propane, 2-methyl-2-(2,2,2-trifluoroethoxy)-
• CAS No.: 80054-67-7
• Molecular Formula: C6H11F3O
• Molecular Weight: 156.148
• Mol file: 80054-67-7.mol

Synonyms:

Chemical Property of Propane, 2-methyl-2-(2,2,2-trifluoroethoxy)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Propane, 2-methyl-2-(2,2,2-trifluoroethoxy)-

There total 4 articles about Propane, 2-methyl-2-(2,2,2-trifluoroethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tertiary butyl chloride (507-20-0) + 2,2,2-trifluoroethanol (75-89-8) → 2-Methyl-2-(2,2,2-trifluoro-ethoxy)-propane (80054-67-7) + tert-butyl alcohol (75-65-0)

Guidance literature:

With water; In acetonitrile; at 25 ℃; Rate constant; Thermodynamic data; solvolytic reaction; role of nucleophilic and other solvation effects; ΔH(activ.), ΔS(activ.); further temp. 39.9 deg C;

DOI:10.1021/jo980109d

Reference yield:

N-isobutyl-N-nitro-O-benzoylhydroxylamine (92844-60-5) → 2-Methyl-2-(2,2,2-trifluoro-ethoxy)-propane (80054-67-7) + tert-butyl alcohol (75-65-0)

Guidance literature:

In water; at 80 ℃; Mechanism; Product distribution; other solvent 1,1,1-Trifluorethanol; different ratios;

DOI:10.1021/jo00199a025

Reference yield:

t-butyl bromide (507-19-7) + 2,2,2-trifluoroethanol (75-89-8) → 2-Methyl-2-(2,2,2-trifluoro-ethoxy)-propane (80054-67-7) + tert-butyl alcohol (75-65-0)

Guidance literature:

With water; at 25 ℃; Rate constant; solvolytic reaction; role of nucleophilic and other solvation effects;

DOI:10.1021/jo980109d

upstream raw materials:

N-isobutyl-N-nitro-O-benzoylhydroxylamine

tertiary butyl chloride

2,2,2-trifluoroethanol

t-butyl bromide

Refernces

• 1、 White, Emil H.,Reefer, John,Erickson, Ronald H.,Dzadzic, Petar M.. "Synthesis and Decomposition of the N-Alkyl-N-nitro-O-benzoylhydroxylamines". . p. 4872 - 4876. Retrieved 2007/10/02.