Lithium 2,6-bis(trifluoromethyl)benzen-1-ide

Base Information

Chemical Name:Lithium 2,6-bis(trifluoromethyl)benzen-1-ide
CAS No.:80426-23-9
Molecular Formula:C₈H₃F₆Li
Molecular Weight:220.043
Hs Code.:
DSSTox Substance ID:DTXSID20560934

Synonyms:80426-23-9;Lithium 2,6-bis(trifluoromethyl)benzen-1-ide;SCHEMBL11612177;DTXSID20560934

Suppliers and Price of Lithium 2,6-bis(trifluoromethyl)benzen-1-ide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Lithium 2,6-bis(trifluoromethyl)benzen-1-ide

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:0
Exact Mass:220.02989750
Heavy Atom Count:15
Complexity:286

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:[Li+].C1=CC(=[C-]C(=C1)C(F)(F)F)C(F)(F)F

Technology Process of Lithium 2,6-bis(trifluoromethyl)benzen-1-ide

There total 1 articles about Lithium 2,6-bis(trifluoromethyl)benzen-1-ide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 402-31-3
1,3-bis(trifluoromethyl)benzene

: 136664-85-2
2,4-(CF₃)2C₆H₃Li

: 80426-23-9
(2,6-bis(trifluoromethyl)-phenyl)lithium

Guidance literature:: With n-butyllithium; In diethyl ether; hexane; at -78 - 20 ℃; for 4h;
DOI:10.1039/b309820f

Reference yield: 57.0%

: 136664-85-2
2,4-(CF₃)2C₆H₃Li

: 7646-78-8
tin(IV) chloride

: 80426-23-9
(2,6-bis(trifluoromethyl)-phenyl)lithium

: 650583-84-9
bis[2,4-bis(trifluoromethyl)phenyl]dichlorostannane

: 650583-85-0
bis[2,6-bis(trifluoromethyl)phenyl]dichlorostannane

Guidance literature:: In diethyl ether; hexane; byproducts: LiCl; (N2); Schlenk technique or glovebox; soln. of mixt. of Li compd. (2 equiv.) in Et2O was added dropwise to soln. of SnCl4 (1 equiv.) in hexane atroom temp. and stirred for 4 h; filtered; solvents removed (vac.); oily residue filtered; filtered-off residue washed (pentane; CH2Cl2); dried (vac.); recrystd. (pentane and Et2O); elem. anal.;
DOI:10.1039/b302544f

Reference yield: 54.0%

: potassium hydrogen difluoride

: 608-28-6
2,6-dimethyliodobenzene

: 80426-23-9
(2,6-bis(trifluoromethyl)-phenyl)lithium

: 73183-34-3
bis(pinacol)diborane

: bis(2,6-bis(trifluoromethyl)phenyl)(4-iodo-3,5-dimethylphenyl)borane

Guidance literature:: 2,6-dimethyliodobenzene; bis(pinacol)diborane; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine; In hexane; at 60 ℃; for 72h; Schlenk technique; Inert atmosphere; Glovebox;

potassium hydrogen difluoride; In methanol; water; at 20 ℃; for 12h; Schlenk technique; Glovebox; Inert atmosphere;

(2,6-bis(trifluoromethyl)-phenyl)lithium; In diethyl ether; at -78 - 20 ℃; for 12h; Schlenk technique; Glovebox; Inert atmosphere;
DOI:10.1002/chem.202001985