Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester

Base Information

• Chemical Name: Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester
• CAS No.: 80472-59-9
• Molecular Formula: C14H14O3S2
• Molecular Weight: 294.395
• Mol file: 80472-59-9.mol

Synonyms:

Chemical Property of Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester

There total 22 articles about Benzenesulfonothioic acid, 4-methyl-, S-(4-methoxyphenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.1%

methoxybenzene (100-66-3) + SS-morpholino 4-toluene(dithioperoxo)sulfonate (84655-87-8) → S-(4-methoxyphenyl) (4-methylbenzene)thiosulfonate (80472-59-9)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 16h; Reagent/catalyst; Solvent; Inert atmosphere;

DOI:10.1021/acs.orglett.0c04289

Reference yield: 93.1%

4,4'-dimethoxyphenyl disulfide (5335-87-5) + sodium 4-methylbenzenesulfinate (824-79-3) → S-(4-methoxyphenyl) (4-methylbenzene)thiosulfonate (80472-59-9)

Guidance literature:

With iodine; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1039/c7cc05868c

Reference yield: 89.0%

4-Methoxybenzenethiol (696-63-9) + sodium 4-methylbenzenesulfonothioate (3753-27-3) → S-(4-methoxyphenyl) (4-methylbenzene)thiosulfonate (80472-59-9)

Guidance literature:

4-Methoxybenzenethiol; With dihydrogen peroxide; sodium iodide; In ethyl acetate; at 20 ℃; for 0.5h;

sodium 4-methylbenzenesulfonothioate; With iodine; In dichloromethane; at 20 ℃;

DOI:10.1002/chem.201900932

upstream raw materials:

morpholino p-toluenesulfonyl sulfide

p-toluenesulfonyl iodide

sodium 4-methoxyphenylthiolate

4,4'-dimethoxyphenyl thiosulfonate

Downstream raw materials:

tert-butyl (3aS,4R,6S,6aR)-6-(2-(4-methoxyphenylthio)propan-2-yl)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-ylcarbamate

3-((4-methoxyphenyl)thio)thiophene

di(p-tolyl) disulfide

2,3-bis<(4-methoxyphenyl)thio>indole

Refernces

• 1、 Kumari, Arram Haritha,Kumar, Jangam Jagadesh,Krishna, Gamidi Rama,Reddy, Raju Jannapu. "Nickel-Catalyzed Difunctionalization of Alkynyl Bromides with Thiosulfonates and N -Arylthio Succinimides: A Convenient Synthesis of 1,2-Thiosulfonylethenes and 1,1-Dithioethenes". supporting information. p. 2850 - 2864. Retrieved 2021/05/18.
• 2、 Huang, Cheng-Mi,Li, Jian,Wang, Shun-Yi,Ji, Shun-Jun. "TFA promoted multi-component reaction of aryldiazonium with sodium metabisulphite and thiols: Construction of thiosulfonate under transition-metal free conditions". supporting information. p. 1923 - 1926. Retrieved 2020/01/13.