8-chloro-1-phenyl-3H-2-benzazepine

Base Information

Chemical Name:8-chloro-1-phenyl-3H-2-benzazepine
CAS No.:81078-22-0
Molecular Formula:C16H12ClN
Molecular Weight:253.731
Hs Code.:
DSSTox Substance ID:DTXSID80533629

Synonyms:8-chloro-1-phenyl-3H-2-benzazepine;81078-22-0;SCHEMBL10991753;DTXSID80533629;HWPXLEMJGRXRKT-UHFFFAOYSA-N

Suppliers and Price of 8-chloro-1-phenyl-3H-2-benzazepine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 8-chloro-1-phenyl-3H-2-benzazepine

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:253.0658271
Heavy Atom Count:18
Complexity:341

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C=CC2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3

Technology Process of 8-chloro-1-phenyl-3H-2-benzazepine

There total 3 articles about 8-chloro-1-phenyl-3H-2-benzazepine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 76049-61-1
3-amino-1-[4-chloro-2-benzoylphenyl]propyne

: 81078-22-0
8-chloro-1-phenyl-3H-2-benzazepine

Guidance literature:: With barium sulfate; palladium 10% on activated carbon; hydrogen;
DOI:10.1016/j.bmcl.2016.02.016

Reference yield:

: 76049-48-4
5-chloro-2-iodobenzophenone

: 81078-22-0
8-chloro-1-phenyl-3H-2-benzazepine

Guidance literature:: Multi-step reaction with 3 steps

1: palladium dichloride; triphenylphosphine; copper(l) iodide; diethylamine

2: methylamine

3: palladium 10% on activated carbon; hydrogen; barium sulfate

With barium sulfate; copper(l) iodide; palladium 10% on activated carbon; hydrogen; diethylamine; triphenylphosphine; methylamine; palladium dichloride;
DOI:10.1016/j.bmcl.2016.02.016

Reference yield:

: 76049-52-0
1-[4-chloro-2-benzoylphenyl]-3-phthalimidopropyne

: 81078-22-0
8-chloro-1-phenyl-3H-2-benzazepine

Guidance literature:: Multi-step reaction with 2 steps

1: methylamine

2: palladium 10% on activated carbon; hydrogen; barium sulfate

With barium sulfate; palladium 10% on activated carbon; hydrogen; methylamine;
DOI:10.1016/j.bmcl.2016.02.016