n-Methyl-4-(methylsulfonyl)-2-nitroaniline

Base Information

Chemical Name:n-Methyl-4-(methylsulfonyl)-2-nitroaniline
CAS No.:30388-44-4
Molecular Formula:C8H10N2O4S
Molecular Weight:230.244
Hs Code.:2921430090
European Community (EC) Number:250-171-2
DSSTox Substance ID:DTXSID80952730
Nikkaji Number:J249.979G
Wikidata:Q82931411
Mol file:30388-44-4.mol

Synonyms:30388-44-4;n-methyl-4-(methylsulfonyl)-2-nitroaniline;N-Methyl-N-[4-(methylsulfonyl)-2-nitrophenyl]amine;N-methyl-4-methylsulfonyl-2-nitroaniline;n-methyl-n-[4-(methylsulphonyl)-2-nitrophenyl]amine;n-methyl-n-[4-methylsulfonyl-2-nitrophenyl]amine;4-Mesyl- N-methyl-2-nitroaniline;EINECS 250-171-2;4-methanesulfonyl-N-methyl-2-nitroaniline;SCHEMBL2245974;DTXSID80952730;MFCD01016949;AKOS008922873;PS-6010;4-(Methanesulfonyl)-N-methyl-2-nitroaniline;CS-0318161;FT-0638919;N-Methyl-4-(methylsulphonyl)-2-nitroaniline;N-Methyl-4-methylsulfonyl-2-nitrobenzenamine;(4-methanesulfonyl-2-nitro-phenyl)-methyl-amine;A820350

Suppliers and Price of n-Methyl-4-(methylsulfonyl)-2-nitroaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Methyl-N-[4-(methylsulfonyl)-2-nitrophenyl]amine
100mg
$ 75.00

Matrix Scientific
N-Methyl-N-[4-(methylsulfonyl)-2-nitrophenyl]amine
1g
$ 174.00

Crysdot
N-Methyl-4-(methylsulfonyl)-2-nitroaniline 95+%
5g
$ 508.00

Atlantic Research Chemicals
N-Methyl-N-[4-(methylsulphonyl)-2-nitrophenyl]amine 95%
1gm:
$ 60.09

American Custom Chemicals Corporation
4-METHANESULFONYL-N-METHYL-2-NITROANILINE 95.00%
500MG
$ 695.31

AK Scientific
N-Methyl-4-(methylsulfonyl)-2-nitroaniline
1g
$ 237.00

AHH
4,6-Dimethoxy-2-[phenyl(piperazin-1-yl)methyl]pyrimidine 98%
5g
$ 330.00

Total 14 raw suppliers

Chemical Property of n-Methyl-4-(methylsulfonyl)-2-nitroaniline

Chemical Property:

Appearance/Colour:yellow powder
Vapor Pressure:8.79E-09mmHg at 25°C
Melting Point:99-102
Refractive Index:1.568
Boiling Point:441.6 °C at 760 mmHg
Flash Point:220.9 °C
PSA：100.37000
Density:1.416 g/cm³
LogP:2.71700
XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:230.03612798
Heavy Atom Count:15
Complexity:330

Purity/Quality:

97% ^*data from raw suppliers

N-Methyl-N-[4-(methylsulfonyl)-2-nitrophenyl]amine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC1=C(C=C(C=C1)S(=O)(=O)C)[N+](=O)[O-]
Uses 1-[alpha-(4,6-Dimethoxypyrimidin-2-yl)benzyl]-piperazine (CAS# 354563-89-6) can be used to prepare isoquinolinone derivatives as NK3 antagonists that are useful in treating psychosis and schizophrenia. It can also be used to modulate cholesterol biosynthetic pathway and for therapeutic uses.

Technology Process of n-Methyl-4-(methylsulfonyl)-2-nitroaniline

There total 6 articles about n-Methyl-4-(methylsulfonyl)-2-nitroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 453-72-5
1-fluoro-4-methanesulfonyl-2-nitrobenzene

: 74-89-5
methylamine

: 30388-44-4
methyl 4-methyl-amino-3-nitrophenyl sulfone

Guidance literature:

Reference yield:

: 97-07-4
1-chloro-4-methanesulfonyl-2-nitrobenzene

: 693-05-0
N-(2-cyanoethyl)-N-methylamine

: 30388-44-4
methyl 4-methyl-amino-3-nitrophenyl sulfone

: 81689-46-5
3-[(4-Methanesulfonyl-2-nitro-phenyl)-methyl-amino]-propionitrile

Guidance literature:: In butan-1-ol; at 118 ℃; for 40h;

Reference yield:

: 98-57-7
4-chlorophenyl methyl sulfone

: 30388-44-4
methyl 4-methyl-amino-3-nitrophenyl sulfone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium nitrate; sulfuric acid / 2 h / 90 °C

2: 3 h / 80 °C

With sulfuric acid; potassium nitrate;
DOI:10.1039/d1nj01019k