Technology Process of Benzenepropanoic acid, b-hydroxy-,
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl ester
There total 1 articles about Benzenepropanoic acid, b-hydroxy-,
3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
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37858-03-0
Acetic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl ester
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830330-63-7
3-hydroxy-3-phenyl-propionic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl ester
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3-phenyl-3-trimethylsilanyloxy-propionic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl ester
- Guidance literature:
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Acetic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl ester;
With
lithium diisopropyl amide;
In
tetrahydrofuran;
at -78 ℃;
for 0.75h;
benzaldehyde;
In
tetrahydrofuran;
at -78 ℃;
for 3h;
chloro-trimethyl-silane;
In
tetrahydrofuran;
at -78 ℃;
DOI:10.3390/90500266
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830330-63-7
3-hydroxy-3-phenyl-propionic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl ester
- Guidance literature:
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With
lithium triethylborohydride;
In
tetrahydrofuran;
at 20 ℃;
for 2h;
DOI:10.3390/90500266
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830330-63-7
3-hydroxy-3-phenyl-propionic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl ester
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830330-65-9
3-hydroxy-3-o-tolyl-propionic acid 3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octyl ester
- Guidance literature:
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Multi-step reaction with 3 steps
1.1: LiHBEt3 / tetrahydrofuran / 2 h / 20 °C
2.1: 78 percent / Et3N / CH2Cl2 / 12 h / 25 °C
3.1: LDA / tetrahydrofuran / 0.75 h / -78 °C
3.2: tetrahydrofuran / 3 h / -78 °C
3.3: 81 percent / tetrahydrofuran / -78 °C
With
lithium triethylborohydride; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane;
DOI:10.3390/90500266
