6-Iodo-2,4-dimethoxyquinazoline

Base Information

Chemical Name:6-Iodo-2,4-dimethoxyquinazoline
CAS No.:830343-15-2
Molecular Formula:C10H9IN2O2
Molecular Weight:316.09500
Hs Code.:
DSSTox Substance ID:DTXSID30472271
Nikkaji Number:J2.141.239B
Wikidata:Q82301098
Mol file:830343-15-2.mol

Synonyms:6-Iodo-2,4-dimethoxyquinazoline;830343-15-2;DTXSID30472271;AKOS015962672

Suppliers and Price of 6-Iodo-2,4-dimethoxyquinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
6-iodo-2,4-dimethoxyquinazoline 95%
1g
$ 632.00

American Custom Chemicals Corporation
6-IODO-2,4-DIMETHOXYQUINAZOLINE 95.00%
5MG
$ 497.51

Alichem
6-Iodo-2,4-dimethoxyquinazoline
1g
$ 538.56

Total 2 raw suppliers

Chemical Property of 6-Iodo-2,4-dimethoxyquinazoline

Chemical Property:

PSA：44.24000
LogP:2.25160
Storage Temp.:2-8°C
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:315.97088
Heavy Atom Count:15
Complexity:218

Purity/Quality:

≥99% ^*data from raw suppliers

6-iodo-2,4-dimethoxyquinazoline 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=NC(=NC2=C1C=C(C=C2)I)OC

Technology Process of 6-Iodo-2,4-dimethoxyquinazoline

There total 3 articles about 6-Iodo-2,4-dimethoxyquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 124-41-4
sodium methylate

: 74173-76-5
2,4-dichloro-6-iodoquinazoline

: 830343-15-2
6-iodo-2,4-dimethoxyquinazoline

Guidance literature:: In methanol; for 18h; Heating;
DOI:10.1021/jo0483973

Reference yield:

: 5326-47-6
2-amino-5-iodobenzoic acid

: 830343-15-2
6-iodo-2,4-dimethoxyquinazoline

Guidance literature:: Multi-step reaction with 3 steps

1: 96 percent / 150 °C

2: 75 percent / phosphorus oxychloride; N,N-diethylaniline / 4 h / Heating

3: 91 percent / methanol / 18 h / Heating

With N,N-diethylaniline; trichlorophosphate; In methanol;
DOI:10.1021/jo0483973

Reference yield:

: 16353-27-8
6-Iodo-1H-quinazoline-2,4-dione

: 830343-15-2
6-iodo-2,4-dimethoxyquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / phosphorus oxychloride; N,N-diethylaniline / 4 h / Heating

2: 91 percent / methanol / 18 h / Heating

With N,N-diethylaniline; trichlorophosphate; In methanol;
DOI:10.1021/jo0483973