2-chloro-N-methyl-5-nitrobenzamide

Base Information

Chemical Name:2-chloro-N-methyl-5-nitrobenzamide
CAS No.:85469-93-8
Molecular Formula:C8H7ClN2O3
Molecular Weight:214.608
Hs Code.:
DSSTox Substance ID:DTXSID70383554
Wikidata:Q82175329
ChEMBL ID:CHEMBL4793930

Synonyms:2-chloro-N-methyl-5-nitrobenzamide;85469-93-8;Benzamide, 2-chloro-N-methyl-5-nitro-;Oprea1_191654;SCHEMBL4361418;CHEMBL4793930;DTXSID70383554;QGEACCYXLCMQFM-UHFFFAOYSA-N;n-methyl-2-chloro-5-nitrobenzamide;2-Chloro N-methyl-5-nitrobenzamide;2-chloro-N-methyl-5-nitro-benzamide;STL140622;AKOS000155004

Suppliers and Price of 2-chloro-N-methyl-5-nitrobenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-chloro-N-methyl-5-nitrobenzamide

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:214.0145198
Heavy Atom Count:14
Complexity:241

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CNC(=O)C1=C(C=CC(=C1)[N+](=O)[O-])Cl

Technology Process of 2-chloro-N-methyl-5-nitrobenzamide

There total 8 articles about 2-chloro-N-methyl-5-nitrobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 8.0%

: 25784-91-2
2-chloro-5-nitrobenzoylchloride

: 74-89-5
methylamine

: 85469-93-8
2-chloro-5-nitro-N-methylbenzamide

Guidance literature:: With triethylamine; In tetrahydrofuran; dichloromethane; at 0 - 20 ℃; Inert atmosphere;
DOI:10.1021/acsmedchemlett.1c00029

Reference yield:

aqueous sodium chloride: aqueous sodium chloride

: 25784-91-2
2-chloro-5-nitrobenzoylchloride

: 85469-93-8
2-chloro-5-nitro-N-methylbenzamide

Guidance literature:: With hydrogenchloride; methylamine hydrochloride; triethylamine; In dichloromethane; ethyl acetate;

Reference yield:

: 2516-96-3
2-chloro-5-nitrobenzoic acid

: 85469-93-8
2-chloro-5-nitro-N-methylbenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / 3 h / Heating

2: acetone / Ambient temperature

With thionyl chloride; In acetone;