N-(4-chlorophenyl)-N,N-diethylamine

Base Information

• Chemical Name: N-(4-chlorophenyl)-N,N-diethylamine
• CAS No.: 2873-89-4
• Molecular Formula: C10H14 Cl N
• Molecular Weight: 183.681
• Hs Code.: 2921420090
• Mol file: 2873-89-4.mol

Synonyms:Aniline,p-chloro-N,N-diethyl- (6CI,7CI,8CI); 4-Chloro-N,N-diethylaniline;4-Chloro-N,N-diethylbenzenamine; N,N-Diethyl-p-chloroaniline;p-Chloro-N,N-diethylaniline

Chemical Property of N-(4-chlorophenyl)-N,N-diethylamine

Chemical Property:

• Vapor Pressure: 407mmHg at 25°C
• Melting Point: 45.5°C
• Refractive Index: 1.6000 (estimate)
• Boiling Point: 42.3°Cat760mmHg
• Flash Point: °C
• PSA: 3.24000
• Density: 0.588g/cm³
• LogP: 3.18620

Purity/Quality:

99% ^*data from raw suppliers

p-Chloro-N,N-diethylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: p-Chloro-N,N-diethylaniline is derived from N,N-Diethylaniline (D443520), which is used as an intermediate in the manufacture of dyes, pharmaceuticals and other chemicals, and also as a reaction catalyst. N-(4-chlorophenyl)-N,N-diethylamine may be genotoxic, due to its effect on increasing sister chromatid exchange.

Technology Process of N-(4-chlorophenyl)-N,N-diethylamine

There total 17 articles about N-(4-chlorophenyl)-N,N-diethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethyl iodide (75-03-6) + N-(p-chlorophenyl)triphenylarsine imide (110802-64-7) → 4-chloro-N,N-diethylaniline (2873-89-4) + C20H20As(3+)*3I(1-)

Guidance literature:

In benzene; for 3h; Heating;

Reference yield: 85.0%

1,3,5-Trioxan (110-88-3) + 4-chloro-aniline (106-47-8) → 4-chloro-N,N-diethylaniline (2873-89-4)

Guidance literature:

With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1248/cpb.c17-00716

Reference yield: 82.0%

4-chloro-aniline (106-47-8) + 2-(2-methoxyethoxy)ethyl ethyl carbonate (214470-03-8) → 4-chloro-N,N-diethylaniline (2873-89-4) + N-ethyl-4-chloro-aniline (13519-75-0)

Guidance literature:

With NaY; at 150 ℃; for 11h;

DOI:10.1021/jo0006728

upstream raw materials:

triethyl phosphate

4-chloro-aniline

ethyl bromide

N-ethyl-4-chloro-aniline

Downstream raw materials:

4-chloro-N-ethyl-N-nitrosoaniline

N,N-Diethyl-p-selenocyanatoaniline

N-ethyl-4-chloro-2-nitro-aniline

N-(4-Chloro-2-nitrophenyl)diethylamine