4-Chloro-N-ethyl-N-nitrosobenzenamine

Base Information

• Chemical Name: 4-Chloro-N-ethyl-N-nitrosobenzenamine
• CAS No.: 1008-93-1
• Molecular Formula: C₈H₉ClN₂O
• Molecular Weight: 184.625
• DSSTox Substance ID: DTXSID101286509
• Nikkaji Number: J903.982A
• Mol file: 1008-93-1.mol

Synonyms:1008-93-1;SCHEMBL10792849;DTXSID101286509;4-Chloro-N-ethyl-N-nitrosobenzenamine

Chemical Property of 4-Chloro-N-ethyl-N-nitrosobenzenamine

Chemical Property:

• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 184.0403406
• Heavy Atom Count: 12
• Complexity: 146

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCN(C1=CC=C(C=C1)Cl)N=O

Technology Process of 4-Chloro-N-ethyl-N-nitrosobenzenamine

There total 11 articles about 4-Chloro-N-ethyl-N-nitrosobenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

N-cyclopropyl-N-ethyl-p-chloroaniline (257946-77-3) → 4-chloro-N-ethyl-N-nitrosoaniline (1008-93-1)

Guidance literature:

With sodium nitrite; In water; acetic acid; at 0 ℃;

DOI:10.1021/jo991104z

Reference yield:

4-chloro-N,N-diethylaniline (2873-89-4) → 4-chloro-N-ethyl-N-nitrosoaniline (1008-93-1) + N-ethyl-4-chloro-2-nitro-aniline (28491-95-4) + N-(4-Chloro-2-nitrophenyl)diethylamine (86309-90-2) + (4-Chloro-2-nitrophenyl)ethylnitrosamine (86309-91-3)

Guidance literature:

With sodium nitrite; In water; acetic acid; at 85 - 90 ℃; for 1.5h; Product distribution; var. of time;

DOI:10.1021/jo00164a023

Reference yield:

4-chloro-N,N-diethylaniline (2873-89-4) → 4-chloro-N-ethyl-N-nitrosoaniline (1008-93-1) + N-(4-Chloro-2-nitrophenyl)diethylamine (86309-90-2)

Guidance literature:

With sodium nitrite; In water; acetic acid; at 85 - 90 ℃; for 0.133333h; Yield given. Yields of byproduct given;

DOI:10.1021/jo00164a023

upstream raw materials:

pyridine

ethanol

tetranitromethane

4-chloro-N,N-diethylaniline