2-(2-Aminophenyl)sulfanylethanol

Base Information

• Chemical Name: 2-(2-Aminophenyl)sulfanylethanol
• CAS No.: 77474-06-7
• Molecular Formula: C8H11 N O S
• Molecular Weight: 169.247
• Hs Code.: 2930909090
• NSC Number: 25622
• DSSTox Substance ID: DTXSID60282365
• Nikkaji Number: J2.516.047I
• Wikidata: Q82016620
• Mol file: 77474-06-7.mol

Synonyms:2-(2-aminophenyl)sulfanylethanol;77474-06-7;NSC25622;SCHEMBL8621805;DTXSID60282365;NSC-25622;AKOS000194502

Chemical Property of 2-(2-Aminophenyl)sulfanylethanol

Chemical Property:

• Vapor Pressure: 0.000155mmHg at 25°C
• Boiling Point: 318°C at 760 mmHg
• Flash Point: 146.1°C
• PSA: 71.55000
• Density: 1.22g/cm³
• LogP: 1.93440
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 169.05613515
• Heavy Atom Count: 11
• Complexity: 110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N)SCCO

Technology Process of 2-(2-Aminophenyl)sulfanylethanol

There total 9 articles about 2-(2-Aminophenyl)sulfanylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

[1,3]-dioxolan-2-one (96-49-1) + 2-amino-benzenethiol (137-07-5) → 2-<(2-Hydroxyethyl)thio>aniline (77474-06-7)

Guidance literature:

With potassium carbonate; In acetonitrile; at 150 ℃; for 5h; Autoclave;

DOI:10.1055/s-0037-1611710

Reference yield: 94.0%

2-((2-nitrophenyl)thio)ethan-1-ol (13287-78-0) → 2-<(2-Hydroxyethyl)thio>aniline (77474-06-7)

Guidance literature:

With hydrazine hydrate; nickel-iron mixed oxide; In isopropyl alcohol; for 0.466667h; Heating;

DOI:10.1002/adsc.200700070

Reference yield: 84.0%

2-amino-benzenethiol (137-07-5) + 2-chloro-ethanol (107-07-3) → 2-<(2-Hydroxyethyl)thio>aniline (77474-06-7)

Guidance literature:

With sodium hydrogencarbonate; In 1,4-dioxane; water; for 48h;

DOI:10.1021/ja00183a039

upstream raw materials:

oxirane

2-amino-benzenethiol

2-Chloronitrobenzene

2-hydroxyethanethiol

Downstream raw materials:

benzoic acid-[2-(2-hydroxy-ethylsulfanyl)-anilide]

2-<(2-Bromoethyl)sulfonyl>aniline hydrobromide

2-<(2-Bromoethyl)sulfinyl>aniline hydrobromide

2-<(2-Bromoethyl)thio>aniline hydrobromide