3-Methylidene-5-phenylpent-4-ynoic acid

Base Information

Chemical Name:3-Methylidene-5-phenylpent-4-ynoic acid
CAS No.:86650-47-7
Molecular Formula:C12H10O2
Molecular Weight:186.21
Hs Code.:
DSSTox Substance ID:DTXSID80523287
Wikidata:Q82389291

Synonyms:86650-47-7;3-METHYLIDENE-5-PHENYLPENT-4-YNOIC ACID;DTXSID80523287

Suppliers and Price of 3-Methylidene-5-phenylpent-4-ynoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-Methylidene-5-phenylpent-4-ynoic acid

Chemical Property:

XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:186.068079557
Heavy Atom Count:14
Complexity:284

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C=C(CC(=O)O)C#CC1=CC=CC=C1

Technology Process of 3-Methylidene-5-phenylpent-4-ynoic acid

There total 1 articles about 3-Methylidene-5-phenylpent-4-ynoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 674-82-8,2130-41-8
4-methyleneoxetan-2-one

: 13984-49-1
(phenylethynyl)zinc chloride

: 86650-47-7
3-(phenylethynyl)-3-butenoic acid

Guidance literature:: With diisobutylaluminium hydride; tetrakis(triphenylphosphine)nickel⁽⁰⁾; In tetrahydrofuran; hexane; for 2h; Ambient temperature;

Reference yield: 70.0%

: 5765-65-1
4-(benzoyloxy)morpholine

: 86650-47-7
3-(phenylethynyl)-3-butenoic acid

: C₁₅H₁₇NO

Guidance literature:: With copper(II) bis(trifluoromethanesulfonate); sodium carbonate; In 1,2-dichloro-ethane; at 90 ℃; for 1h; regioselective reaction;
DOI:10.1021/acscatal.0c03621