6,9,12-Hexadecatrienoic acid, methyl ester, (6Z,9Z,12Z)-

Base Information

• Chemical Name: 6,9,12-Hexadecatrienoic acid, methyl ester, (6Z,9Z,12Z)-
• CAS No.: 873108-80-6
• Molecular Formula: C17H28O2
• Molecular Weight: 264.408
• Mol file: 873108-80-6.mol

Synonyms:6,9,12-Hexadecatrienoic acid,methyl ester,(6Z,9Z,12Z);6,9,12-hexadecatrienoic acid methyl ester;

Chemical Property of 6,9,12-Hexadecatrienoic acid, methyl ester, (6Z,9Z,12Z)-

Chemical Property:

• PSA: 26.30000
• LogP: 4.96870

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6,9,12-Hexadecatrienoic acid, methyl ester, (6Z,9Z,12Z)-

There total 2 articles about 6,9,12-Hexadecatrienoic acid, methyl ester, (6Z,9Z,12Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + bathymodiolamide A → methyl n-dodecanoate (111-82-0) + hexadecanoic acid methyl ester (112-39-0) + methyl (6Z,9Z,12Z)-hexadeca-6,9,12-trienoate (873108-80-6)

Guidance literature:

With sodium methylate; for 2h;

Reference yield:

methanol (67-56-1) + (2S)-1-O-5,8,11,14,17-eicosapentaenoyl-2-O-6,9,12-hexadecatrienoyl-3-O-[β-D-galactopyranosyl]glycerol (1038401-98-7) → (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-icosapentaenoic acid methyl ester (2734-47-6) + methyl (6Z,9Z,12Z)-hexadeca-6,9,12-trienoate (873108-80-6) + (2R)-1-O-β-D-galactopyranosylglycerol (16232-91-0)

Guidance literature:

With sodium methylate; at 20 ℃; for 3h;

DOI:10.1021/np800124k

Reference yield: 88.0%

methyl (6Z,9Z,12Z)-hexadeca-6,9,12-trienoate (873108-80-6) → 6,9,12-hexadecatrienoic acid (29428-96-4)

Guidance literature:

With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 18h; Inert atmosphere;

DOI:10.1021/acs.joc.0c02726

upstream raw materials:

methanol

(2S)-1-O-5,8,11,14,17-eicosapentaenoyl-2-O-6,9,12-hexadecatrienoyl-3-O-[β-D-galactopyranosyl]glycerol

Downstream raw materials:

6,9,12-hexadecatrienoic acid