1,5-DIPHENYL-3-(4-METHOXYPHENYL)-1H-PYRAZOLE

Base Information

• Chemical Name: 1,5-DIPHENYL-3-(4-METHOXYPHENYL)-1H-PYRAZOLE
• CAS No.: 33045-40-8
• Molecular Formula: C22H18 N2 O
• Molecular Weight: 326.398
• Hs Code.: 2933199090
• Mol file: 33045-40-8.mol

Synonyms:Pyrazole,3-(p-methoxyphenyl)-1,5-diphenyl- (7CI,8CI); NSC 409743

Chemical Property of 1,5-DIPHENYL-3-(4-METHOXYPHENYL)-1H-PYRAZOLE

Chemical Property:

• Vapor Pressure: 6.39E-10mmHg at 25°C
• Boiling Point: 507.5°Cat760mmHg
• Flash Point: 260.7°C
• PSA: 27.05000
• Density: 1.11g/cm³
• LogP: 5.21490

Purity/Quality:

99% ^*data from raw suppliers

1,5-DIPHENYL-3-(4-METHOXYPHENYL)-1H-PYRAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5-DIPHENYL-3-(4-METHOXYPHENYL)-1H-PYRAZOLE

There total 32 articles about 1,5-DIPHENYL-3-(4-METHOXYPHENYL)-1H-PYRAZOLE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-(4-methoxyphenyl)-4,5-dihydro-1,5-diphenyl-1H-pyrazole (1450-62-0) → 3-p-anisyl-1,5-diphenylpyrazole (33045-40-8)

Guidance literature:

With bismuth (III) nitrate pentahydrate; acetic acid; for 0.0125h; microwave irradiation;

DOI:10.1080/00397910500214136

Reference yield: 91.0%

phenylhydrazine (100-63-0) + 3-(4-methoxyphenyl)-1-phenylprop-2-yn-1-one (20442-66-4) → 3-p-anisyl-1,5-diphenylpyrazole (33045-40-8)

Guidance literature:

In ethanol; Heating;

Reference yield: 86.0%

trans-4'-methoxychalcone (22966-19-4) + phenylhydrazine (100-63-0) → 3-p-anisyl-1,5-diphenylpyrazole (33045-40-8)

Guidance literature:

palladium on activated charcoal; K-10 montmorillonite; In dichloromethane; at 160 ℃; for 0.5h; microwave irradiation;

DOI:10.1055/s-2007-982545

upstream raw materials:

1-(p-methoxyphenyl)-3-phenyl-2,3-epoxy-1-propanone

acetic acid

phenylhydrazine

acetic anhydride

Downstream raw materials:

4-iodo-3-(4-methoxyphenyl)-1,5-diphenyl-1H-pyrazole