4-Phenylpiperidine hydrochloride

Base Information

• Chemical Name: 4-Phenylpiperidine hydrochloride
• CAS No.: 10272-49-8
• Molecular Formula: C11H15 N . Cl H
• Molecular Weight: 197.708
• Hs Code.: 2933399090
• European Community (EC) Number: 233-617-0
• DSSTox Substance ID: DTXSID20145467
• ChEMBL ID: CHEMBL2011546
• Mol file: 10272-49-8.mol

Synonyms:4-phenylpiperidine hydrochloride;10272-49-8;4-Phenylpiperidinium chloride;4-phenylpiperidine hcl;4-Phenyl-piperidine hydrochloride;4-phenylpiperidinehydrochloride;4-PHENYL-PIPERIDINE HCL;4-phenylpiperidine;hydrochloride;CHEMBL2011546;EINECS 233-617-0;4-Phenyl piperidine hydrochloride;Piperidine, 4-phenyl-, hydrochloride (1:1);AMY724;SCHEMBL1481633;4-phenyl-piperidin hydrochloride;DTXSID20145467;MFCD01632527;4-phenyl-piperidine hydrochloride salt;AKOS015897961;AC-1948;CS-W001274;SB41533;DS-13410;FT-0687364;EN300-28898;A26724;SR-01000514382;SR-01000514382-1;Z235351197;4-Phenylpiperdine HCL;4-Phenylpiperdine hydrochloride

Chemical Property of 4-Phenylpiperidine hydrochloride

Chemical Property:

• Vapor Pressure: 0.0126mmHg at 25°C
• Melting Point: 164-165℃
• Boiling Point: 259.9°Cat760mmHg
• Flash Point: 113°C
• PSA: 12.03000
• Density: g/cm³
• LogP: 3.28440
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 197.0971272
• Heavy Atom Count: 13
• Complexity: 121

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Phenylpiperidinehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CNCCC1C2=CC=CC=C2.Cl

Technology Process of 4-Phenylpiperidine hydrochloride

There total 9 articles about 4-Phenylpiperidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,2,3,6-tetrahydro-4-phenylpyridine hydrochloride (43064-12-6) → 4-phenylpiperidine hydrochloride (10272-49-8)

Guidance literature:

carbon palladium; In methanol;

Reference yield: 97.0%

1-benzyl-4-phenyl-1,2,5,6-tetrahydropirydine hydrochloride (94163-98-1) → 4-phenylpiperidine hydrochloride (10272-49-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethanol; for 44h;

DOI:10.1016/j.bmcl.2012.01.122

Reference yield:

4-phenylpiperidine (771-99-3) → 4-phenylpiperidine hydrochloride (10272-49-8)

Guidance literature:

With hydrogenchloride; In water; ethyl acetate; for 0.5h;

upstream raw materials:

1-benzyl-4-phenyl-1,2,5,6-tetrahydropirydine hydrochloride

1,2,3,6-tetrahydro-4-phenylpyridine hydrochloride

bromobenzene

1-phenylmethyl-4-piperidone

Downstream raw materials:

1-methyl-4-phenylpiperidine

metilen-bis-<1,1'-(fenil-4)-piperidina>

5-chloro-2-[3-(4-phenyl-1-piperidyl)propyl]-4(3H)-quinazolinone

4-phenyl-N-[3-(1-pyrrolidinylmethyl)-7-quinolinyl]-1-piperidinecarboxamide

Refernces

• 1、 -. "POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS". Page/Page column 42; 43. . Retrieved 2018/07/29.
• 2、 -. "Novel aminophenyl piperazine or aminophenyl piperidine derivatives inhibiting prenyl transferase proteins and method for preparing same". Page/Page column 38. . Retrieved 2008/06/13.