1-(4-Chlorobenzyl)pyrrolidine-2,5-dione

Base Information

Chemical Name:1-(4-Chlorobenzyl)pyrrolidine-2,5-dione
CAS No.:91349-11-0
Molecular Formula:C11H10ClNO2
Molecular Weight:223.659
Hs Code.:
NSC Number:32127
DSSTox Substance ID:DTXSID90283562
Wikidata:Q82018172

Synonyms:91349-11-0;1-(4-chlorobenzyl)pyrrolidine-2,5-dione;NSC32127;CBMicro_014334;DTXSID90283562;SMSF0004715;NSC-32127;BIM-0014200.P001;EU-0043844;SR-01000484183;SR-01000484183-1

Suppliers and Price of 1-(4-Chlorobenzyl)pyrrolidine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 1-(4-Chlorobenzyl)pyrrolidine-2,5-dione

Chemical Property:

Vapor Pressure:2.3E-07mmHg at 25°C
Boiling Point:423.1°Cat760mmHg
Flash Point:209.7°C
Density:1.371g/cm³
XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:223.0400063
Heavy Atom Count:15
Complexity:256

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1=O)CC2=CC=C(C=C2)Cl

Technology Process of 1-(4-Chlorobenzyl)pyrrolidine-2,5-dione

There total 4 articles about 1-(4-Chlorobenzyl)pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 108-30-5
succinic acid anhydride

: 104-86-9
4-chlorobenzylamine

: 91349-11-0
1-[(4-chlorophenyl)methyl]-2,5-pyrrolidinedione

Guidance literature:: With niobium(V) oxide; In neat (no solvent); at 140 ℃; for 15h;
DOI:10.1002/cctc.201501172

Reference yield: 69.0%

: 110-63-4
Butane-1,4-diol

: 104-86-9
4-chlorobenzylamine

: 91349-11-0
1-[(4-chlorophenyl)methyl]-2,5-pyrrolidinedione

Guidance literature:: With C₂₁H₃₅BrMnN₂O₂P; potassium hydride; In toluene; for 40h; Schlenk technique; Glovebox; Inert atmosphere; Reflux; Green chemistry;
DOI:10.1021/jacs.7b08341

Reference yield: 67.0%

: 623-03-0
4-Cyanochlorobenzene

: 110-63-4
Butane-1,4-diol

: 91349-11-0
1-[(4-chlorophenyl)methyl]-2,5-pyrrolidinedione

Guidance literature:: With dihydridotetrakis(triphenylphosphine)ruthenium; sodium hydride; 1,3-di(propan-2-yl)-1H-imidazol-3-ium bromide; In benzene; at 80 ℃; for 18h; Glovebox; Inert atmosphere; Reflux;
DOI:10.1021/ol501835t