6-(4-Methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole

Base Information

Chemical Name:6-(4-Methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole
CAS No.:87532-36-3
Molecular Formula:C₁₈H₁₆N₂OS
Molecular Weight:308.404
Hs Code.:
ChEMBL ID:CHEMBL17132
DSSTox Substance ID:DTXSID40542954
Wikidata:Q82419764

Synonyms:87532-36-3;6-(4-methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b]thiazole;6-(4-Methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole;CHEMBL17132;SCHEMBL11375954;DTXSID40542954

Suppliers and Price of 6-(4-Methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 6-(4-Methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:308.09833431
Heavy Atom Count:22
Complexity:366

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(N3CCSC3=N2)C4=CC=CC=C4

Technology Process of 6-(4-Methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole

There total 5 articles about 6-(4-Methoxyphenyl)-5-phenyl-2,3-dihydroimidazo[2,1-b][1,3]thiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 24845-40-7
2-(4-methoxyphenyl)acetophenone

: 87532-36-3
5-phenyl-6-(4-methoxyphenyl)-2,3-dihydroimidazo<2,1-b>thiazole

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / Br₂ / CCl₄ / Irradiation

2: molecular sieves (3A) / acetonitrile / Ambient temperature

With 3 A molecular sieve; bromine; In tetrachloromethane; acetonitrile;
DOI:10.1021/jm00367a014

Reference yield:

: 4693-91-8
4-methoxyphenyl-acetic chloride

: 87532-36-3
5-phenyl-6-(4-methoxyphenyl)-2,3-dihydroimidazo<2,1-b>thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: 5.22 g / AlCl₃ / CH₂Cl₂ / Ambient temperature

2: 65 percent / Br₂ / CCl₄ / Irradiation

3: molecular sieves (3A) / acetonitrile / Ambient temperature

With aluminium trichloride; 3 A molecular sieve; bromine; In tetrachloromethane; dichloromethane; acetonitrile;
DOI:10.1021/jm00367a014

Reference yield:

: 71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1
benzene

: 87532-36-3
5-phenyl-6-(4-methoxyphenyl)-2,3-dihydroimidazo<2,1-b>thiazole

Guidance literature:: Multi-step reaction with 3 steps

1: 5.22 g / AlCl₃ / CH₂Cl₂ / Ambient temperature

2: 65 percent / Br₂ / CCl₄ / Irradiation

3: molecular sieves (3A) / acetonitrile / Ambient temperature

With aluminium trichloride; 3 A molecular sieve; bromine; In tetrachloromethane; dichloromethane; acetonitrile;
DOI:10.1021/jm00367a014