2-chloroethyl 4-chlorobenzoate

Base Information

• Chemical Name: 2-chloroethyl 4-chlorobenzoate
• CAS No.: 1078-32-6
• Molecular Formula: C9H8 Cl2 O2
• Molecular Weight: 219.067
• Mol file: 1078-32-6.mol

Synonyms:Benzoicacid, p-chloro-, 2-chloroethyl ester (6CI,7CI,8CI);2-(p-Chlorobenzoyloxy)-1-chloroethane; 2-Chloroethyl 4-chlorobenzoate;2-Chloroethyl p-chlorobenzoate; NSC 406650

Chemical Property of 2-chloroethyl 4-chlorobenzoate

Chemical Property:

• Vapor Pressure: 0.00157mmHg at 25°C
• Boiling Point: 295°Cat760mmHg
• Flash Point: 124.7°C
• Density: 1.31g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-chloroethyl 4-chlorobenzoate

There total 6 articles about 2-chloroethyl 4-chlorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-(4-chlorophenyl)-2-hydroxyethanone (27993-56-2) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → 2-chloroethyl 4-chlorobenzoate (1078-32-6)

Guidance literature:

With 18-crown-6 ether; oxygen; potassium carbonate; In water; at 80 ℃; for 10h; under 760.051 Torr;

DOI:10.1002/anie.201207206

Reference yield: 74.0%

4-chlorobenzaldehyde (104-88-1) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → 2-chloroethyl 4-chlorobenzoate (1078-32-6)

Guidance literature:

4-chlorobenzaldehyde; With tert.-butylhydroperoxide; potassium carbonate; In water; dimethyl sulfoxide; at 120 ℃; for 5h;

1,2-dichloro-ethane; at 60 ℃; for 3h;

DOI:10.1039/c3ra43615b

Reference yield: 70.0%

bis(4-chlorobenzoyl)peroxide (94-17-7) + 1,2-dichloro-ethane (107-06-2,52399-93-6) → 2-chloroethyl 4-chlorobenzoate (1078-32-6)

Guidance literature:

With 1,10-Phenanthroline; oxygen; copper diacetate; sodium t-butanolate; In dimethyl sulfoxide; at 80 ℃; for 24h;

DOI:10.1016/j.tet.2013.11.085

upstream raw materials:

4-chloro-benzoyl chloride

2-chloro-ethanol

1-(4-chlorophenyl)-2-hydroxyethanone

1,2-dichloro-ethane

Downstream raw materials:

2-diethylaminoethyl 4-chlorobenzoate

para-chlorobenzoic acid