4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-3-(phenylmethoxy)-

Base Information

Chemical Name:4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-3-(phenylmethoxy)-
CAS No.:88187-01-3
Molecular Formula:C23H18O4
Molecular Weight:358.394
Hs Code.:
DSSTox Substance ID:DTXSID40364794
Wikidata:Q82148945

Synonyms:88187-01-3;4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-3-(phenylmethoxy)-;DTXSID40364794;3-(Benzyloxy)-2-(4-methoxyphenyl)-4H-chromen-4-one

Suppliers and Price of 4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-3-(phenylmethoxy)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-3-(phenylmethoxy)-

Chemical Property:

XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:358.12050905
Heavy Atom Count:27
Complexity:541

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(C(=O)C3=CC=CC=C3O2)OCC4=CC=CC=C4

Technology Process of 4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-3-(phenylmethoxy)-

There total 2 articles about 4H-1-Benzopyran-4-one, 2-(4-methoxyphenyl)-3-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 6889-78-7
4'-(methoxy)-3-hydroxyflavone

: 100-44-7
benzyl chloride

: 88187-01-3
3-(benzyloxy)-2-(4-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: 4'-(methoxy)-3-hydroxyflavone; With tetrabutylammomium bromide; potassium carbonate; In N,N-dimethyl-formamide; at 50 - 60 ℃; for 0.5h;

benzyl chloride; at 50 - 60 ℃;
DOI:10.1080/07391102.2020.1803136

Reference yield:

: 118-93-4,104809-67-8
o-hydroxyacetophenone

: 123-11-5
4-methoxy-benzaldehyde

: 88187-01-3
3-(benzyloxy)-2-(4-methoxyphenyl)-4H-chromen-4-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / methanol; water / 0.5 h

1.2: 20 °C

1.3: 1 h / 20 °C

2.1: potassium carbonate; tetrabutylammomium bromide / N,N-dimethyl-formamide / 0.5 h / 50 - 60 °C

2.2: 50 - 60 °C

With tetrabutylammomium bromide; potassium carbonate; sodium hydroxide; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1080/07391102.2020.1803136