Tetraethyl propane-1,2,2,3-tetracarboxylate

Base Information

• Chemical Name: Tetraethyl propane-1,2,2,3-tetracarboxylate
• CAS No.: 7460-75-5
• Molecular Formula: C15H24O8
• Molecular Weight: 332.351
• European Community (EC) Number: 231-247-4
• NSC Number: 404217
• UNII: DP2DBE4KD7
• DSSTox Substance ID: DTXSID60225575
• Nikkaji Number: J278.863B
• Wikidata: Q83104593
• Mol file: 7460-75-5.mol

Synonyms:Tetraethyl propane-1,2,2,3-tetracarboxylate;7460-75-5;DP2DBE4KD7;EINECS 231-247-4;NSC-404217;NSC404217;UNII-DP2DBE4KD7;SCHEMBL10992850;DTXSID60225575;AKOS024340917;NSC 404217;1,2,2,3-Propanetetracarboxylic acid tetraethyl ester;1,2,2,3-Propanetetracarboxylic acid, tetraethyl ester;3,3-BIS(ETHOXYCARBONYL)GLUTARIC ACID DIETHYL ESTER;1,2,2,3-TETRAETHYL 1,2,2,3-PROPANETETRACARBOXYLATE;1,2,2,3-PROPANETETRACARBOXYLIC ACID, 1,2,2,3-TETRAETHYL ESTER

Chemical Property of Tetraethyl propane-1,2,2,3-tetracarboxylate

Chemical Property:

• Vapor Pressure: 2.07E-06mmHg at 25°C
• Boiling Point: 393.8°Cat760mmHg
• Flash Point: 169.6°C
• Density: 1.145g/cm³
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 14
• Exact Mass: 332.14711772
• Heavy Atom Count: 23
• Complexity: 389

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)CC(CC(=O)OCC)(C(=O)OCC)C(=O)OCC

Technology Process of Tetraethyl propane-1,2,2,3-tetracarboxylate

There total 6 articles about Tetraethyl propane-1,2,2,3-tetracarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

ethyl bromoacetate (105-36-2) + diethyl malonate (105-53-3) → propane-1,2,2,3-tetracarboxylic acid tetraethyl ester (7460-75-5)

Guidance literature:

With aluminum oxide; sodium ethanolate; for 20h;

Reference yield:

chloroacetic acid ethyl ester (105-39-5) + diethyl malonate (105-53-3) → propane-1,2,2,3-tetracarboxylic acid tetraethyl ester (7460-75-5)

Guidance literature:

With sodium ethanolate; In ethanol;

DOI:10.1021/jo01053a012

Reference yield:

chloroacetic acid ethyl ester (105-39-5) → propane-1,2,2,3-tetracarboxylic acid tetraethyl ester (7460-75-5)

Guidance literature:

With ethanol;

upstream raw materials:

sodium diethylmalonate

chloroacetic acid ethyl ester

ethyl 2-chloro-3-oxo-butyrate

diethyl malonate

Downstream raw materials:

tricarallylic acid