Benzaldehyde, 4-methoxy-2-(trimethylsilyl)-

Base Information

Chemical Name:Benzaldehyde, 4-methoxy-2-(trimethylsilyl)-
CAS No.:88932-60-9
Molecular Formula:C11H16O2Si
Molecular Weight:208.332
Hs Code.:
DSSTox Substance ID:DTXSID30452351
Wikidata:Q82272925

Synonyms:88932-60-9;4-METHOXY-2-(TRIMETHYLSILYL)BENZALDEHYDE;Benzaldehyde, 4-methoxy-2-(trimethylsilyl)-;DTXSID30452351

Suppliers and Price of Benzaldehyde, 4-methoxy-2-(trimethylsilyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Benzaldehyde, 4-methoxy-2-(trimethylsilyl)-

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:208.091956283
Heavy Atom Count:14
Complexity:198

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=C(C=C1)C=O)[Si](C)(C)C

Technology Process of Benzaldehyde, 4-methoxy-2-(trimethylsilyl)-

There total 7 articles about Benzaldehyde, 4-methoxy-2-(trimethylsilyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: N,N-diisopropyl-4-methoxy-2-(trimethylsilyl)benzamide

: 88932-60-9
4-Methoxy-2-(trimethylsilyl)benzaldehyde

Guidance literature:: N,N-diisopropyl-4-methoxy-2-(trimethylsilyl)benzamide; With 2,6-di-tert-butyl-4-methylpyridine; trifluoromethanesulfonic acid ethyl ester; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

With lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; dichloromethane; at -78 ℃; for 4h; Inert atmosphere;
DOI:10.1021/acs.joc.7b02868

Reference yield:

: 75-77-4
chloro-trimethyl-silane

: 123-11-5
4-methoxy-benzaldehyde

: 88932-60-9
4-Methoxy-2-(trimethylsilyl)benzaldehyde

Guidance literature:: 4-methoxy-benzaldehyde; With n-butyllithium; N,N,N-trimethylethane-1,2-diamine; In tetrahydrofuran; hexane; at -20 ℃; for 24.25h; Inert atmosphere;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at -40 - 23 ℃; for 1h; Inert atmosphere;
DOI:10.1055/s-0031-1291048

Reference yield:

: 88932-58-5
2-(4-Methoxy-2-(trimethylsilyl)phenyl)-4,4-dimethyl-2-oxazoline

: 88932-60-9
4-Methoxy-2-(trimethylsilyl)benzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / acetonitrile / 12 h / Heating

2: 1) NaBH₄, 2) 2N-HCl / 1) ethanol, 0-5 deg C, 2 h, 2) methanol, heating, 30 min

With hydrogenchloride; sodium tetrahydroborate; In acetonitrile;
DOI:10.1021/jo00181a021