2-(4-Methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine

Base Information

Chemical Name:2-(4-Methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine
CAS No.:89185-49-9
Molecular Formula:C13H12N4O
Molecular Weight:240.264
Hs Code.:
DSSTox Substance ID:DTXSID20569684
Nikkaji Number:J374.543K
Wikidata:Q82456883

Synonyms:2-(4-methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine;89185-49-9;DTXSID20569684;AKOS015956099;CS-0302747;EN300-235285;F1967-0081

Suppliers and Price of 2-(4-Methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 0 raw suppliers

Chemical Property of 2-(4-Methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine

Chemical Property:

PSA：65.44000
LogP:2.56830
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:240.10111102
Heavy Atom Count:18
Complexity:280

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=C(N3C=CC=NC3=N2)N

Technology Process of 2-(4-Methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine

There total 5 articles about 2-(4-Methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 109-12-6
2-aminopyrimidine

: 7677-24-9
trimethylsilyl cyanide

: 123-11-5
4-methoxy-benzaldehyde

: 89185-49-9
2-(4-methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine

Guidance literature:: With zinc(II) oxide; In ethanol; for 0.2h; Sonication;
DOI:10.1016/j.ultsonch.2012.09.006

Reference yield:

: 31555-35-8
2-(p-methoxyphenyl)imidazo[1,2-a]pyrimidine

: 89185-49-9
2-(4-methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium nitrite / acetic acid

2: H₂ / Raney nickel

With hydrogen; sodium nitrite; nickel; In acetic acid;
DOI:10.1248/cpb.40.1170

Reference yield:

: 2632-13-5
2-Bromo-4'-methoxyacetophenone

: 89185-49-9
2-(4-methoxyphenyl)imidazo[1,2-a]pyrimidin-3-amine

Guidance literature:: Multi-step reaction with 3 steps

1: 1,2-dimethoxy-ethane / 48 h / Heating

2: sodium nitrite / acetic acid

3: H₂ / Raney nickel

With hydrogen; sodium nitrite; nickel; In 1,2-dimethoxyethane; acetic acid;
DOI:10.1248/cpb.40.1170