3-Methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine

Base Information

Chemical Name:3-Methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine
CAS No.:89193-00-0
Molecular Formula:C15H14N2O
Molecular Weight:238.28400
Hs Code.:
DSSTox Substance ID:DTXSID90528288
Wikidata:Q82397773

Synonyms:3-Methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine;89193-00-0;DTXSID90528288

Suppliers and Price of 3-Methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine

Chemical Property:

PSA：26.53000
LogP:3.31830
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:238.110613074
Heavy Atom Count:18
Complexity:278

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CN2C1=NC(=C2OC)C3=CC=CC=C3

Technology Process of 3-Methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine

There total 3 articles about 3-Methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 67-56-1
methanol

: 885-89-2
8-methyl-2-phenylimidazo[1,2-a]pyridine

: 89193-00-0
3-methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine

Guidance literature:: With Rose Bengal lactone; In N,N-dimethyl-formamide; at 20 ℃; for 6h; Irradiation;
DOI:10.1021/acs.joc.7b02582

Reference yield:

: 25142-28-3
2-phenyl-1H-imidazo<1,2-a>pyridinium-3-olate

: 89193-00-0
3-methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 35 deg C, 10 min, 2.) 35 deg C, 15 min

2: 1.) THF, hexane, -70 deg C, 30 min, 2.) -70 deg C

With sodium hydride;
DOI:10.1055/s-1983-30593

Reference yield:

: 89192-94-9
3-Methoxy-2-phenylimidazo<1,2-a>pyridine

: 74-88-4
methyl iodide

: 89193-00-0
3-methoxy-8-methyl-2-phenylimidazo[1,2-a]pyridine

: 89192-99-4
3-Methoxy-5-methyl-2-phenyl-imidazo[1,2-a]pyridine

Guidance literature:: Yield given. Multistep reaction. Yields of byproduct given; 1.) THF, hexane, -70 deg C, 30 min, 2.) -70 deg C;
DOI:10.1055/s-1983-30593