N-[2-(chloromethyl)phenyl]acetamide

Base Information

Chemical Name:N-[2-(chloromethyl)phenyl]acetamide
CAS No.:90562-37-1
Molecular Formula:C9H10ClNO
Molecular Weight:183.637
Hs Code.:
DSSTox Substance ID:DTXSID101292203

Synonyms:N-[2-(chloromethyl)phenyl]acetamide;90562-37-1;N-(2-(Chloromethyl)phenyl)acetamide;SCHEMBL6475322;DTXSID101292203;AKOS017529173;CID 14368468;EN300-6479268

Suppliers and Price of N-[2-(chloromethyl)phenyl]acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of N-[2-(chloromethyl)phenyl]acetamide

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:183.0450916
Heavy Atom Count:12
Complexity:161

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=CC=C1CCl

Technology Process of N-[2-(chloromethyl)phenyl]acetamide

There total 14 articles about N-[2-(chloromethyl)phenyl]acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 20939-77-9
2-acetamidobenzyl alcohol

: 90562-37-1
N-(2-chloromethylphenyl)acetamide

Guidance literature:: With thionyl chloride; In tetrahydrofuran; at -40 - 20 ℃;
DOI:10.1002/hlca.201400078

Reference yield:

: 75-44-5
phosgene

: 5395-04-0
1,1'-carbonyldipiperidine

: 90562-37-1
N-(2-chloromethylphenyl)acetamide

Guidance literature:: With chloroform; toluene;

Reference yield:

: 95982-61-9
o-nitro-N-benzyl(benzylamine)

: 90562-37-1
N-(2-chloromethylphenyl)acetamide

Guidance literature:: Multi-step reaction with 6 steps

1: 80.7 percent / Et₃N / diethyl ether / 5 h / Ambient temperature

2: 68.4 percent / NaBH₄ / methanol; H₂O / 4 h / Ambient temperature

3: 87.3 percent / H₂ / Raney-Ni / ethyl acetate / 16 h / 760 Torr / Ambient temperature

4: 88.8 percent / H₂SO₄ / CH₂Cl₂ / 0.5 h / 5 - 7 °C

5: 80.5 percent / glacial acetic acid / 4 h / Ambient temperature

6: 79 percent Chromat_. / benzene / 18 h / Heating

With sodium tetrahydroborate; sulfuric acid; hydrogen; acetic acid; triethylamine; nickel; In methanol; diethyl ether; dichloromethane; water; ethyl acetate; benzene;