5395-04-0

Basic information

• Product Name: 1,1'-CARBONYLDIPIPERIDINE
• Synonyms: 1-(1-Piperidinylcarbonyl)piperidine;1,1’-carbonyldi-piperidin;N,N,N',N'-Bis(cyclopentamethylene)urea;N,N,N',N'-Bispentamethyleneurea;n,n’-carbonylbis(piperidine);N,N-Bis-pentamethylene urea;N,N'-Carbonylbis(piperidine);Piperidine, 1,1'-carbonyldi-
• CAS NO: 5395-04-0
• Molecular Formula: C₁₁H₂₀N₂O
• Molecular Weight: 196.29
• EINECS: 226-407-5
• Product Categories: API intermediates;Building Blocks;C11;Chemical Synthesis;Heterocyclic Building Blocks;Piperidines
• Mol File: 5395-04-0.mol
• Article Data: 25

Chemical Properties

• Melting Point: 44-47 °C(lit.)
• Boiling Point: 296-298 °C(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.0014 (rough estimate)
• Vapor Pressure: 0.00139mmHg at 25°C
• Refractive Index: 1.4620 (estimate)
• Storage Temp.: Refrigerator
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: -0.35±0.20(Predicted)
• CAS DataBase Reference: 1,1'-CARBONYLDIPIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1'-CARBONYLDIPIPERIDINE(5395-04-0)
• EPA Substance Registry System: 1,1'-CARBONYLDIPIPERIDINE(5395-04-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 24/25
• WGK Germany: 3
• RTECS: TM5950000
• Hazardous Substances Data: 5395-04-0(Hazardous Substances Data)

Usage

Chemical Properties

Faintly yellow crystals

Uses

Different sources of media describe the Uses of 5395-04-0 differently. You can refer to the following data:
1. Reactant for synthesis of:? ;Bis(guanidine) ligands for tuning of copper(I) dioxygen reactivity1? ;Diaminocarbene- and Fischer-carbene complexes of palladium and nickel by oxidative insertion2? ;Neodymium and europium complexes with amides and cyclic aminoxides3? ;Bis(pentamethylene)urea complexes of lanthanide nitrates4? ;Europium complexes for luminescence studies5? ;Tetra(amino)methanes6
2. 1,1''-Carbonyldipiperidine is a urea.

InChI:InChI=1/C11H20N2O/c14-11(12-7-3-1-4-8-12)13-9-5-2-6-10-13/h1-10H2

Upstream product

• 110-89-4 piperidine 
• 75-44-5 phosgene 
• 201230-82-2 carbon monoxide 
• 67-56-1 methanol 
• 650-51-1 sodium trichloroacetate 
• 67-66-3 chloroform 
• 6091-44-7 piperidine hydrochloride 
• 2591-86-8 N-Formylpiperidine 
• 1450882-02-6 C₂₅H₂₂P⁽¹⁺⁾*C₂₀H₂₅Cl₃N₃OPt^(1-) 
• 124-38-9 carbon dioxide 
• 21050-95-3 N-chlorobenzotriazole 
• 503441-11-0 2-trifluoromethoxyethyl trifluoromethoxyacetate 
• 13939-69-0 piperidine carbamoyl chloride 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 120-72-9 indole 
• 5012-77-1 Cyclohexyl-(di-piperidin-1-yl-methylene)-amine 
• 110-89-4 piperidine 
• 67-56-1 methanol 

Relevant articles and documents

OXIDATIVE CARBONYLATION OF PIPERIDINE IN THE PRESENCE OF PALLADIUM(II)-COPPER(II) CATALYTIC SYSTEM.

A kinetic study on oxidative carbonylation of piperidine to give 1,1 prime -carbonyldipiperidine in the presence of Pd(II) and Cu(II) complexes at 40 degree C has been investigated.

CARBONATE DERIVATIVE PRODUCTION METHOD

The objective of the present invention is to provide a method for producing a carbonate derivative in a safe and efficient manner. The method for producing a carbonate derivative according to the present invention is characterized in comprising irradiating light on a composition containing a C1-4 halogenated hydrocarbon having one or more kinds of halogen atoms selected from the group consisting of a chlorine atom, a bromine atom and an iodine atom, a nucleophilic functional group-containing compound and the specific base in the presence of oxygen.

Organic ligand and solvent free oxidative carbonylation of amine over Pd/TiO2 with unprecedented activity

A highly active Pd/TiO2 catalyst system was prepared and applied in the oxidative carbonylation of amines to ureas with ultra-low Pd content under organic ligand and solvent free conditions. The catalytic turnover frequencies (TOFs, moles of amines converted per mole of Pd per h) were 126000 and 250000 h-1 for the production of diphenylurea and dibenzylurea, respectively. An expanded substrate scope including the electron-rich and electron-deficient anilines, primary aliphatic amines, secondary amines was also established. This work offers a straightforward, step economic, and green methodology for the efficient synthesis of valuable ureas.