4-Isothiazolecarboxamide, N-[[[[3-chloro-5-methyl-4-[[2-[(phenylmethyl)amino]acetyl]amino]phenyl] methyl]amino]iminomethyl]-3-(4-methoxyphenyl)-5-methyl-

Base Information

Chemical Name:4-Isothiazolecarboxamide, N-[[[[3-chloro-5-methyl-4-[[2-[(phenylmethyl)amino]acetyl]amino]phenyl] methyl]amino]iminomethyl]-3-(4-methoxyphenyl)-5-methyl-
CAS No.:917387-70-3
Molecular Formula:C30H31ClN6O3S
Molecular Weight:591.134
Hs Code.:

4-Isothiazolecarboxamide,
N-[[[[3-chloro-5-methyl-4-[[2-[(phenylmethyl)amino]acetyl]amino]phenyl]
methyl]amino]iminomethyl]-3-(4-methoxyphenyl)-5-methyl-

Synonyms:

Suppliers and Price of 4-Isothiazolecarboxamide, N-[[[[3-chloro-5-methyl-4-[[2-[(phenylmethyl)amino]acetyl]amino]phenyl] methyl]amino]iminomethyl]-3-(4-methoxyphenyl)-5-methyl-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Isothiazolecarboxamide, N-[[[[3-chloro-5-methyl-4-[[2-[(phenylmethyl)amino]acetyl]amino]phenyl] methyl]amino]iminomethyl]-3-(4-methoxyphenyl)-5-methyl-

Chemical Property:

Purity/Quality:

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Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-Isothiazolecarboxamide, N-[[[[3-chloro-5-methyl-4-[[2-[(phenylmethyl)amino]acetyl]amino]phenyl] methyl]amino]iminomethyl]-3-(4-methoxyphenyl)-5-methyl-

There total 7 articles about 4-Isothiazolecarboxamide, N-[[[[3-chloro-5-methyl-4-[[2-[(phenylmethyl)amino]acetyl]amino]phenyl] methyl]amino]iminomethyl]-3-(4-methoxyphenyl)-5-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₅H₃₉ClN₆O₅S

: 917387-70-3
N-(amino(4-(2-(benzylamino)acetamido)-3,5-dichlorobenzylamino)methylene)-3-(4-methoxyphenyl)-5-methylisothiazole-4-carboxamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;
DOI:10.1021/jm300931y

Reference yield:

: 158296-69-6
4-amino-3-chloro-5-methylbenzonitrile

: 917387-70-3
N-(amino(4-(2-(benzylamino)acetamido)-3,5-dichlorobenzylamino)methylene)-3-(4-methoxyphenyl)-5-methylisothiazole-4-carboxamide

Guidance literature:: Multi-step reaction with 5 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 5 h / -20 - 65 °C

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

3: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere

4: N-ethyl-N,N-diisopropylamine / methanol; dichloromethane / 20 °C

5: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With lithium aluminium tetrahydride; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1021/jm300931y

Reference yield:

: 917388-79-5
tert-butyl N-(3-(4-methoxyphenyl)-5-methylisothiazole-4-carbonyl)(methylthio)carbonoimidoylcarbamate

: 917387-70-3
N-(amino(4-(2-(benzylamino)acetamido)-3,5-dichlorobenzylamino)methylene)-3-(4-methoxyphenyl)-5-methylisothiazole-4-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1: N-ethyl-N,N-diisopropylamine / dichloromethane / 20 °C

2: triethylamine / dichloromethane / 2 h / 0 °C / Inert atmosphere

3: N-ethyl-N,N-diisopropylamine / methanol; dichloromethane / 20 °C

4: trifluoroacetic acid / dichloromethane / 1 h / 20 °C

With triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; In methanol; dichloromethane;
DOI:10.1021/jm300931y