Butanoicacid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

Base Information

• Chemical Name: Butanoicacid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
• CAS No.: 69171-62-6
• Molecular Formula: C10H22O3Si
• Molecular Weight: 218.368
• Mol file: 69171-62-6.mol

Synonyms:4-[(1,1-Dimethylethyl)dimethylsilyl]oxy]butanoicacid;4-[(tert-Butyldimethylsilanyl)oxy]butyric acid;

Chemical Property of Butanoicacid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

Chemical Property:

• Vapor Pressure: 0.00162mmHg at 25°C
• Refractive Index: 1.437
• Boiling Point: 273.1 °C at 760 mmHg
• Flash Point: 119 °C
• PSA: 46.53000
• Density: 0.947 g/cm³
• LogP: 2.87300

Purity/Quality:

99% ^*data from raw suppliers

4-[(tert-butyldimethylsilyl)oxy]butanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Butanoicacid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-

There total 1 articles about Butanoicacid, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxybutanoic acid (591-81-1) + tert-butyldimethylsilyl chloride (18162-48-6) → 4-(tert-butyl(dimethyl)silanyloxy)butyric acid (69171-62-6)

Guidance literature:

With pyridine; In chloroform;

Reference yield: 99.0%

4-(tert-butyl(dimethyl)silanyloxy)butyric acid (69171-62-6) + C37H44F2N8O3 → C47H64F2N8O5Si

Guidance literature:

With dmap; p-toluenesulfonyl chloride; In tetrahydrofuran; at 5 - 20 ℃; for 24h;

DOI:10.1021/op010230d

Reference yield: 90.0%

4-(tert-butyl(dimethyl)silanyloxy)butyric acid (69171-62-6) + (S)-4-Benzyl-2-oxazolidinone (90719-32-7) → (S)-4-benzyl-3-[4-(tert-butyldimethylsilanyloxy)butanoyl]oxazolidin-2-one (936731-49-6)

Guidance literature:

4-(tert-butyl(dimethyl)silanyloxy)butyric acid; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at -78 ℃; for 1h;

(S)-4-Benzyl-2-oxazolidinone; With lithium chloride; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1002/asia.201700555

upstream raw materials:

4-hydroxybutanoic acid

tert-butyldimethylsilyl chloride

Downstream raw materials:

C₂₅H₄₂O₆Si

4-Hydroxy-butyric acid (3E,5E,7E)-7-methyl-9-oxo-3-[(E)-2-(2,6,6-trimethyl-cyclohex-1-enyl)-vinyl]-nona-3,5,7-trienyl ester

4-(tert-butyl(dimethyl)silanyloxy)butyric acid phenyl ester

4-(tert-butyl(dimethyl)silanyloxy)-2-((6-chloropyridin-3-yl)methyl)butyric acid phenyl ester

Refernces