(2S)-BOC-2-AMINO-5-HEXENOIC ACID METHYL ESTER

Base Information

Chemical Name:(2S)-BOC-2-AMINO-5-HEXENOIC ACID METHYL ESTER
CAS No.:92136-57-7
Molecular Formula:C12H21NO4
Molecular Weight:243.303
Hs Code.:
Mol file:92136-57-7.mol

Synonyms:methyl (3R)-t-butoxycarbonylaminohex-5-enoate;2-tert-Butoxycarbonylamino-hex-5-enoic acid methyl ester;

Suppliers and Price of (2S)-BOC-2-AMINO-5-HEXENOIC ACID METHYL ESTER

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
(2S)-BOC-2-AMINO-5-HEXENOICACIDMETHYLESTER 95
1g
$ 1833.00

American Custom Chemicals Corporation
(2S)-BOC-2-AMINO-5-HEXENOIC ACID METHYL ESTER 95.00%
5MG
$ 502.03

Total 4 raw suppliers

Chemical Property of (2S)-BOC-2-AMINO-5-HEXENOIC ACID METHYL ESTER

Chemical Property:

Boiling Point:335.5±42.0 °C(Predicted)
PKA:11.14±0.46(Predicted)
PSA：64.63000
Density:1.022±0.06 g/cm3(Predicted)
LogP:2.40980

Purity/Quality:

97% ^*data from raw suppliers

(2S)-BOC-2-AMINO-5-HEXENOICACIDMETHYLESTER 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S)-BOC-2-AMINO-5-HEXENOIC ACID METHYL ESTER

There total 40 articles about (2S)-BOC-2-AMINO-5-HEXENOIC ACID METHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 93267-04-0,170848-34-7,889670-02-4
N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester

: 106-95-6
allyl bromide

: 92136-57-7
(S)-2-tert-butoxycarbonylamino-hex-5-enoic acid methyl ester

Guidance literature:: N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester; With chloro-trimethyl-silane; ethylene dibromide; zinc; In N,N-dimethyl-formamide; at 60 ℃; for 0.333333h; Inert atmosphere;

With copper(l) cyanide; lithium chloride; In N,N-dimethyl-formamide; at -55 - 0 ℃; Inert atmosphere;

allyl bromide; In N,N-dimethyl-formamide; at -55 - 0 ℃; Inert atmosphere;
DOI:10.1021/jo4001492

Reference yield: 93.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 208522-13-8
(S)-2-N-(tert-butoxycarbonyl)-2-amino-5-hexenoic acid

: 92136-57-7
(S)-2-tert-butoxycarbonylamino-hex-5-enoic acid methyl ester

Guidance literature:: In ethanol; at 20 ℃; for 0.5h;
DOI:10.1021/ol062026m

Reference yield: 90.0%

: 93267-04-0,170848-34-7,889670-02-4
N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester

: 107-05-1
3-chloroprop-1-ene

: 92136-57-7
(S)-2-tert-butoxycarbonylamino-hex-5-enoic acid methyl ester

Guidance literature:: N-(tert-butoxycarbonyl)-L-3-iodoalanine methyl ester; With zinc; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 3h; Inert atmosphere; Schlenk technique;

3-chloroprop-1-ene; With copper(I) bromide; In N,N-dimethyl-formamide; at -15 ℃; for 0.25h; Inert atmosphere; Schlenk technique;
DOI:10.1021/ja507166g